DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fkbp12 and fkbp4

DIOPT Version :9

Sequence 1:	NP_523792.2	Gene:	Fkbp12 / 37214	FlyBaseID:	FBgn0013954	Length:	108	Species:	Drosophila melanogaster
Sequence 2:	XP_005173673.1	Gene:	fkbp4 / 321795	ZFINID:	ZDB-GENE-030131-514	Length:	450	Species:	Danio rerio

Alignment Length:	94	Identity:	53/94 - (56%)
Similarity:	67/94 - (71%)	Gaps:	0/94 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 GDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQLSVGQRAKL 75
            |.|:..|..|.||.|||.|||.||::|||||||.:.|.|.:|||:||:.||.|||.:.:|:..:|
Zfish    36 GTGTELPMIGDKVFVHYVGTLLDGSQFDSSRDRGEKFSFELGKGQVIKAWDIGVATMKIGEICQL 100

  Fly    76 ICSPDYAYGSRGHPGVIPPNSTLTFDVEL 104
            .|.|:||||:.|.|..||||:||.|.|||
Zfish   101 TCKPEYAYGAAGSPPKIPPNATLLFQVEL 129

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fkbp12	NP_523792.2	FkpA	<2..107	CDD:223619	53/94 (56%)
fkbp4	XP_005173673.1	FKBP_C	38..129	CDD:278674	50/90 (56%)
		ppisom_GldI	<153..249	CDD:132555
		TPR repeat	269..293	CDD:276809
		TPR_16	270..348	CDD:290168
		TPR repeat	305..343	CDD:276809
		TPR_11	316..379	CDD:290150
		TPR_1	316..347	CDD:278916
		TPR repeat	348..376	CDD:276809
		TPR_1	349..381	CDD:278916
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0545
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100299
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.710