DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fkbp12 and Fkbp4

DIOPT Version :9

Sequence 1:NP_523792.2 Gene:Fkbp12 / 37214 FlyBaseID:FBgn0013954 Length:108 Species:Drosophila melanogaster
Sequence 2:NP_001178792.1 Gene:Fkbp4 / 260321 RGDID:628729 Length:458 Species:Rattus norvegicus


Alignment Length:105 Identity:56/105 - (53%)
Similarity:67/105 - (63%) Gaps:0/105 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     2 GVQVVPIAPGDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQ 66
            ||..|....|.|:.....|.:|.|||||.|.||||||||.||...|.|.:||||||:.||..||.
  Rat    32 GVLKVIKREGTGTETAMIGDRVFVHYTGWLLDGTKFDSSLDRKDKFSFDLGKGEVIKAWDIAVAT 96

  Fly    67 LSVGQRAKLICSPDYAYGSRGHPGVIPPNSTLTFDVELLK 106
            :.||:...:.|.|:|||||.|.|..||||:||.|:|||.:
  Rat    97 MKVGEVCHITCKPEYAYGSAGSPPKIPPNATLVFEVELFE 136

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp12NP_523792.2 FkpA <2..107 CDD:223619 56/105 (53%)
Fkbp4NP_001178792.1 FKBP_C 43..134 CDD:278674 50/90 (56%)
Interaction with tubulin 267..400
TPR_11 274..349 CDD:290150
TPR repeat 274..301 CDD:276809
TPR repeat 306..348 CDD:276809
TPR_1 321..352 CDD:278916
TPR_11 322..384 CDD:290150
TPR repeat 353..381 CDD:276809
TPR_2 354..386 CDD:285020
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 423..458
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_100299
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.710

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