DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Fkbp12 and FKBP8

DIOPT Version :9

Sequence 1:NP_523792.2 Gene:Fkbp12 / 37214 FlyBaseID:FBgn0013954 Length:108 Species:Drosophila melanogaster
Sequence 2:NP_036313.3 Gene:FKBP8 / 23770 HGNCID:3724 Length:413 Species:Homo sapiens


Alignment Length:99 Identity:34/99 - (34%)
Similarity:51/99 - (51%) Gaps:6/99 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly     8 IAPG-DGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVAQLSVGQ 71
            :.|| .||:.|..||.||||...:|::||:.....:    ..||:|..:||:..|..|..:.||:
Human   107 LVPGPPGSSRPVKGQVVTVHLQTSLENGTRVQEEPE----LVFTLGDCDVIQALDLSVPLMDVGE 167

  Fly    72 RAKLICSPDYAYGSRG-HPGVIPPNSTLTFDVEL 104
            .|.:.....|.||.:| ....|||::.|..:|.|
Human   168 TAMVTADSKYCYGPQGSRSPYIPPHAALCLEVTL 201

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp12NP_523792.2 FkpA <2..107 CDD:223619 34/99 (34%)
FKBP8NP_036313.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..68
FKBP_C 113..202 CDD:278674 32/93 (34%)
TPR_11 222..304 CDD:290150
TPR 1 222..255
TPR repeat 231..267 CDD:276809
TPR repeat 272..302 CDD:276809
TPR 2 273..306
TPR_11 274..338 CDD:290150
TPR 3 307..340
TPR 307..340 CDD:197478
TPR repeat 307..335 CDD:276809
TPR repeat 341..369 CDD:276809
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.