DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fkbp12 and Fkbp14

DIOPT Version :9

Sequence 1:NP_523792.2 Gene:Fkbp12 / 37214 FlyBaseID:FBgn0013954 Length:108 Species:Drosophila melanogaster
Sequence 2:NP_705801.1 Gene:Fkbp14 / 231997 MGIID:2387639 Length:211 Species:Mus musculus


Alignment Length:93 Identity:40/93 - (43%)
Similarity:58/93 - (62%) Gaps:4/93 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    18 KNGQKVTVHYTGTLD-DGTKFDSSRDRN--KPFKFTIGKGEVIRGWDEGVAQLSVGQRAKLICSP 79
            |.|..:.|||.|.|: ||:.|.|:...|  :|..||:|..||::|||:|:..:.||::.||...|
Mouse    43 KGGDLMLVHYEGYLEKDGSLFHSTHKHNNGQPVWFTLGILEVLKGWDQGLKGMCVGEKRKLTVPP 107

  Fly    80 DYAYGSRGHPGVIPPNSTLTFDVELLKV 107
            ...||..| .|.|||.|||.|:::||::
Mouse   108 ALGYGKEG-KGKIPPESTLIFNIDLLEI 134

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp12NP_523792.2 FkpA <2..107 CDD:223619 40/91 (44%)
Fkbp14NP_705801.1 FKBP_C 38..132 CDD:278674 38/89 (43%)
EF-hand_7 141..204 CDD:290234
EFh 142..204 CDD:298682
Prevents secretion from ER. /evidence=ECO:0000255|PROSITE-ProRule:PRU10138 208..211
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.810

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