DRSC/TRiP Functional Genomics Resources

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Protein Alignment Fkbp12 and FKBP1B

DIOPT Version :9

Sequence 1:NP_523792.2 Gene:Fkbp12 / 37214 FlyBaseID:FBgn0013954 Length:108 Species:Drosophila melanogaster
Sequence 2:NP_004107.1 Gene:FKBP1B / 2281 HGNCID:3712 Length:108 Species:Homo sapiens


Alignment Length:108 Identity:76/108 - (70%)
Similarity:90/108 - (83%) Gaps:0/108 - (0%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGVQVVPIAPGDGSTYPKNGQKVTVHYTGTLDDGTKFDSSRDRNKPFKFTIGKGEVIRGWDEGVA 65
            |||::..|:||||.|:||.||...|||||.|.:|.||||||||||||||.|||.|||:|::||.|
Human     1 MGVEIETISPGDGRTFPKKGQTCVVHYTGMLQNGKKFDSSRDRNKPFKFRIGKQEVIKGFEEGAA 65

  Fly    66 QLSVGQRAKLICSPDYAYGSRGHPGVIPPNSTLTFDVELLKVE 108
            |:|:||||||.|:||.|||:.|||||||||:||.||||||.:|
Human    66 QMSLGQRAKLTCTPDVAYGATGHPGVIPPNATLIFDVELLNLE 108

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Fkbp12NP_523792.2 FkpA <2..107 CDD:223619 74/104 (71%)
FKBP1BNP_004107.1 FKBP_C 13..105 CDD:395196 66/91 (73%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146999
Domainoid 1 1.000 154 1.000 Domainoid score I4258
eggNOG 1 0.900 - - E1_COG0545
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 178 1.000 Inparanoid score I4030
Isobase 00.000 Not matched by this tool.
OMA 1 1.010 - - QHG53716
OrthoDB 1 1.010 - - D1328688at2759
OrthoFinder 1 1.000 - - FOG0001019
OrthoInspector 1 1.000 - - otm40945
orthoMCL 1 0.900 - - OOG6_100299
Panther 1 1.100 - - LDO PTHR10516
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R449
SonicParanoid 1 1.000 - - X1229
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
User_Submission 00.000 Not matched by this tool.
1615.800

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