Protein Alignment CG10474 and AGA

DIOPT Version :10

• Sequence 1: NP_611404.1
• Gene: CG10474 / 37211
• FlyBaseID: FBgn0034427
• Length: 341
• Species: Drosophila melanogaster
• Sequence 2: NP_000018.2
• Gene: AGA / 175
• HGNCID: 318
• Length: 346
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 167/331 - (50%)
• Similarity: 212/331 - (64%)
• Gaps: 21/331 - (6%)

  Fly     1 MVINTWPFAEAKKEAWRLLNVKKGGLGQTRSAVVGGISMCEKLQCAKTVGYGGNPDERGDTSLDA 65
            :|:|||||..|.:.|||.|    ...|....||..|.:|||:.||..:||:||:|||.|:|:|||
Human    29 LVVNTWPFKNATEAAWRAL----ASGGSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDA 89

  Fly    66 LLMDGGTMEVGAVGDLRRIRSAIKVAQHVLEHTLHTLLVGDGADEFANAMGLQYESLNSEDNIES 130
            ::|||.||:||||||||||::||.||:.|||||.||||||:.|..||.:||...|.|::..:...
Human    90 MIMDGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQAL 154

  Fly   131 LKNWTRHNCQPNFWRNVHPDPRTSCGPYQP--LVTWD-PNAKQS--DRIEIGPDNHDTITMAAID 190
            ..:|...|||||:||||.|||...||||:|  ::..| |..|::  ||      .||||.|..|.
Human   155 HSDWLARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDR------GHDTIGMVVIH 213

  Fly   191 EEGHIHVGTSTNGLRYTLPGRVGDASIPGSAAYADNEVGAAVTTGDGDILMRFLPSLLAVEAMRA 255
            :.|||..||||||:::.:.|||||:.|||:.||||:..|||..||:||||||||||..|||.||.
Human   214 KTGHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRR 278

  Fly   256 GKTPAEAVELVIQRIQKHVKYFEVAVIVANRLGTYAVRCHGTGMARDNGKFAYMV--SSPGQPVR 318
            |:.|..|.:.||.|||||...|..|||.||..|:|...|:......   :|::||  |...||..
Human   279 GEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFT---QFSFMVYNSEKNQPTE 340

  Fly   319 TESVEC 324
             |.|:|
Human   341 -EKVDC 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10474	NP_611404.1	Glycosylasparaginase	1..312	CDD:271335	161/317 (51%)
AGA	NP_000018.2	Glycosylasparaginase	29..332	CDD:271335	161/315 (51%)