DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10474 and Aga

DIOPT Version :9

Sequence 1:NP_611404.1 Gene:CG10474 / 37211 FlyBaseID:FBgn0034427 Length:341 Species:Drosophila melanogaster
Sequence 2:NP_001005847.1 Gene:Aga / 11593 MGIID:104873 Length:346 Species:Mus musculus


Alignment Length:328 Identity:163/328 - (49%)
Similarity:210/328 - (64%) Gaps:15/328 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MVINTWPFAEAKKEAWRLLNVKKGGLGQTRSAVVGGISMCEKLQCAKTVGYGGNPDERGDTSLDA 65
            :|:|||||..|.:.||..|   ..| |....||..|.::|||.||..|||:||:|||.|:|:|||
Mouse    29 LVVNTWPFKNATEAAWWTL---LSG-GSALDAVENGCAVCEKEQCDGTVGFGGSPDEGGETTLDA 89

  Fly    66 LLMDGGTMEVGAVGDLRRIRSAIKVAQHVLEHTLHTLLVGDGADEFANAMGLQYESLNSEDNIES 130
            ::|||..|:|||||.||||::||.||:.|||||.|||||||.|.:||.:||...|.|:::.:.:.
Mouse    90 MIMDGTAMDVGAVGGLRRIKNAIGVARRVLEHTTHTLLVGDSATKFAESMGFTNEDLSTKTSRDL 154

  Fly   131 LKNWTRHNCQPNFWRNVHPDPRTSCGPYQPLVTWDPNAKQS---DRIEIGPDNHDTITMAAIDEE 192
            ..:|...|||||:||||.|||...||||:|    ....|||   .:.|:...:||||.|..|.:.
Mouse   155 HSDWLSRNCQPNYWRNVIPDPSKYCGPYKP----SGFLKQSISPHKEEVDIHSHDTIGMVVIHKT 215

  Fly   193 GHIHVGTSTNGLRYTLPGRVGDASIPGSAAYADNEVGAAVTTGDGDILMRFLPSLLAVEAMRAGK 257
            ||...||||||:::.:||||||:.|||:.||||:..|||..|||||.|:|||||..|||.||.|.
Mouse   216 GHTAAGTSTNGIKFKIPGRVGDSPIPGAGAYADDTAGAAAATGDGDTLLRFLPSYQAVEYMRGGD 280

  Fly   258 TPAEAVELVIQRIQKHVKYFEVAVIVANRLGTYAVRCHGTGMARDNGKFAYMVSSPGQPVRTE-S 321
            .||.|.:.||.||||:...|..|||.|:..|:|...|:......   :|::|||:......|| .
Mouse   281 DPAIACQKVILRIQKYYPNFFGAVICASVNGSYGAACNKLPTFT---QFSFMVSNSLHNEPTEKK 342

  Fly   322 VEC 324
            |:|
Mouse   343 VDC 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10474NP_611404.1 Glycosylasparaginase 1..312 CDD:271335 158/313 (50%)
AgaNP_001005847.1 Glycosylasparaginase 29..332 CDD:271335 158/313 (50%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P20933 234..237 2/2 (100%)
Substrate binding. /evidence=ECO:0000250|UniProtKB:P20933 257..260 2/2 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167831662
Domainoid 1 1.000 320 1.000 Domainoid score I1234
eggNOG 1 0.900 - - E1_COG1446
Hieranoid 00.000 Not matched by this tool.
Homologene 1 1.000 - - H13
Inparanoid 1 1.050 342 1.000 Inparanoid score I2326
Isobase 1 0.950 - 0 Normalized mean entropy S3395
OMA 1 1.010 - - QHG58368
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0004212
OrthoInspector 1 1.000 - - otm43013
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR10188
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 1 1.000 - - X3475
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1312.810

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