DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG11906 and M1BP

DIOPT Version :9

Sequence 1:	NP_611402.2	Gene:	CG11906 / 37209	FlyBaseID:	FBgn0034425	Length:	634	Species:	Drosophila melanogaster
Sequence 2:	NP_649825.1	Gene:	M1BP / 41042	FlyBaseID:	FBgn0037621	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	345	Identity:	67/345 - (19%)
Similarity:	123/345 - (35%)	Gaps:	75/345 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   236 CRVLNEASYDEEAPSRAIRSSRIYYCRHCDAEFETLISKRQHERMKHQQRYP---CDLCEAQLDT 297
            |||..:.:.::.:|....||:    .:..| ..|.|...    |:::....|   |:.|..:|.:
  Fly    13 CRVCAKYASNKRSPKLFERSN----TKMID-NIEALTGL----RLENYGCLPDQICECCSMELAS 68

  Fly   298 KYEWEMHHTICQAKQEALAIVEQQEAG------------QTVMTSRVPRACSMRSRSRACSEAWD 350
            ..:.. ...|...::..|.:.|:|..|            ..|.|.:.|..          .|.:.
  Fly    69 AVKLR-ERCIAAQRELLLGLTEEQRQGISAFYRAAVMGEDIVQTVKTPDD----------DEVYA 122

  Fly   351 RYD---MDEEEEDEEDEEIESGGEELE-----EGEEDAMYARRMNFTGDWIVNHSRSNSNSAGNL 407
            .|.   ::|.:|:.:|.::|......|     .||:||                 .|....|...
  Fly   123 TYQEIVLEEPKEEIDDTKVEYDNTYYEVAEGHAGEDDA-----------------ASLIEEADYD 170

  Fly   408 SLLYGDYGMVETHMTTDKEYDLYLLDLLKTQVRLKSFTCFTPDCGYQTDTLVALMKHDYMEHWKM 472
            |::..|....:| :..|::.:|.:.|:....|             |.:|..||::.:...:.::.
  Fly   171 SIMAEDEEQQQT-LELDEDTELIVGDVNDAYV-------------YDSDDEVAVLDNVLDDEYEH 221

  Fly   473 SWFYCHKCGDVFTSKVFLDYHMHLQNRGLYICHKCREEFELQHQLDRHFQLHRKGINYHCNFCRL 537
            ......||......||..|........|:|||.:|....:.:...:.|.:.||....:.|..|:.
  Fly   222 ENIVVKKCSLPPKPKVRSDDARRRGTGGVYICEQCGNHIKGRMAFELHCRRHRGDKQFGCELCQS 286

  Fly   538 EFLSEAKLLAHCKK-LGHSP 556
            .|.:.::|..|.:| .|..|
  Fly   287 RFCTTSELKRHMRKHTGERP 306

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG11906	NP_611402.2	None
M1BP	NP_649825.1	zf-AD	13..84	CDD:214871	15/80 (19%)
		C2H2 Zn finger	253..273	CDD:275368	3/19 (16%)
		COG5048	276..>331	CDD:227381	8/31 (26%)
		C2H2 Zn finger	281..301	CDD:275368	5/19 (26%)
		zf-H2C2_2	293..317	CDD:290200	5/14 (36%)
		C2H2 Zn finger	309..329	CDD:275368
		zf-H2C2_2	324..346	CDD:290200
		C2H2 Zn finger	337..357	CDD:275368
		zf-H2C2_2	350..372	CDD:290200
		C2H2 Zn finger	365..383	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24388
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100