Protein Alignment tbrd-2 and SPT7

DIOPT Version :9

• Sequence 1: NP_611401.2
• Gene: tbrd-2 / 37207
• FlyBaseID: FBgn0034423
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_009637.1
• Gene: SPT7 / 852373
• SGDID: S000000285
• Length: 1332
• Species: Saccharomyces cerevisiae
• Alignment Length: 706
• Identity: 134/706 - (18%)
• Similarity: 222/706 - (31%)
• Gaps: 229/706 - (32%)

  Fly    37 YFKKHLLDEARKKK------------------------------YALDFLEPVDTEALMVPTYYT 71
            |..|||:.:.||.:                              ::..||..|....  .|.|:.
Yeast   418 YELKHLIMDVRKNRSKWTSDERIGQEELYEACEKVVLELRNYTEHSTPFLNKVSKRE--APNYHQ 480

  Fly    72 VIHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYRKGQMLEKFFHKKLRGM 136
            :|.:.||:.|::|::::..|.|..|.:.|...|..||..:
Yeast   481 IIKKSMDLNTVLKKLKSFQYDSKQEFVDDIMLIWKNCLTY------------------------- 520

  Fly   137 PSGPEVPCNRDPKAVGRPRTNAPSSAQTERKCRELLKKLQSIT--NQTDAMTRNFFSNKWDSLQK 199
                    |.||....|....|     .::|..:|::.:.:||  |:.|             |:|
Yeast   521 --------NSDPSHFLRGHAIA-----MQKKSLQLIRMIPNITIRNRAD-------------LEK 559

  Fly   200 KV-----DRQYFKSVNEFCLHVDGCFRKYHEPAKILYERVFNQPAAWCTSMNGN-SSLESALNAA 258
            ::     |:.|.....|   .|.|..||           ..|..|......||. |..:|:....
Yeast   560 EIEDMEKDKDYELDEEE---EVAGSGRK-----------GLNMGAHMLAKENGKVSEKDSSKTVK 610

  Fly   259 DLNELLAAAKLTVNSLMQCVQMPGSGEPLTAKSLVETFCDTLNKMINKMEAG-----------QR 312
            |      .|....:.|...:......:..||.|.|     |:::.:||.|..           :.
Yeast   611 D------EAPTNDDKLTSVIPEGEKEKDKTASSTV-----TVHENVNKNEIKENGKNEEQDMVEE 664

  Fly   313 NSPNPSSSKRQKMSPEQETDLVQGEFKPAMELLSGNEIDNLMAVSIESSDDEAIDASMRITDADR 377
            :|....|||....:.:...|.:|.:.....|....||.:       |..|||..|..|  .|:..
Yeast   665 SSKTEDSSKDADAAKKDTEDGLQDKTAENKEAGENNEEE-------EDDDDEDEDEDM--VDSQS 720

  Fly   378 CATQKLFAKLPTNAMKEIIHMVQQIEGFSSENCGDLSFDVKGLATDTMIMMKSAVTKATRAHSKL 442
            ...:|                        .::..||.           |.:...||...||...|
Yeast   721 YLLEK------------------------DDDRDDLE-----------ISVWKTVTAKVRAEICL 750

  Fly   443 KLKDMQPSEKEGLQRALQSQLVNITRMLNKNRRRCGPLINFRNKNNTANNVVRKRATAPLTAKLK 507
            |..:...:.|  |....::.|.|..||     :|...|. ...|...|....|::..
Yeast   751 KRTEYFKNGK--LNSDSEAFLKNPQRM-----KRFDQLF-LEYKEQKALESYRQKIE-------- 799

  Fly   508 PLQANVMAPQLGAGVVETHNLSDTSDDDVSAPVKLSAIGGTPMRNLPINSNPLQMQPIRSPPK-- 570
              |.::|  :.|.|.|    |....||.:......|..|.......|   |.:::...|...:
Yeast   800 --QNSIM--KNGFGTV----LKQEDDDQLQFHNDHSLNGNEAFEKQP---NDIELDDTRFLQEYD 853

  Fly   571 ----LPHVVELQMSSSSSSESEMKS-----KSGRLSRSRSRSMSDTKLRPRSNSSAS-------- 618
                :|.:|...:::.:..:.|..|     ::|...:||..:..|..|.|:.|.:.:
Yeast   854 ISNAIPDIVYEGVNTKTLDKMEDASVDRMLQNGINKQSRFLANKDLGLTPKMNQNITLIQQIRHI 918

  Fly   619 ------SRSNSSSSSGSNAGSSSGSRSRSSSSSSSSSNNSSESNDSSDVEVVPNVP 668
                  .|...|..|..|      |||..::..::...|.:..:||.|::.|..:|
Yeast   919 CHKISLIRMLQSPLSAQN------SRSNPNAFLNNHIYNYTIIDDSLDIDPVSQLP 968

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	23/128 (18%)
SPT7	NP_009637.1	COG5076	282..680	CDD:227408	64/339 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860