Protein Alignment tbrd-2 and BDF2

DIOPT Version :9

• Sequence 1: NP_611401.2
• Gene: tbrd-2 / 37207
• FlyBaseID: FBgn0034423
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_010213.1
• Gene: BDF2 / 851488
• SGDID: S000002228
• Length: 638
• Species: Saccharomyces cerevisiae
• Alignment Length: 635
• Identity: 137/635 - (21%)
• Similarity: 215/635 - (33%)
• Gaps: 210/635 - (33%)

  Fly     6 PLSVKLKLPNRVQPEFIP-HPGMAGRYTNKL-----------HYFKKHLLDE---ARKKKYALDF 55
            |:|:.    |...||..| ||....|.|...           .:..|:||..   .::.|.|..|
Yeast    98 PISIS----NASTPESFPEHPLGLERETEPALEAEMEAEELPPHQSKYLLSSIKATKRLKDARPF 158

  Fly    56 LEPVDTEALMVPTYYTVIHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYR 120
            |:|||..||.:|.|:..:..|||:..|..::|.|.|.||.:..:|||.::.||..||.....:..
Yeast   159 LKPVDPIALNIPHYFNYVQTPMDLSLIETKLQGNVYHSVEQVTSDFKTMVDNCLNFNGPESSISS 223

  Fly   121 KGQMLEKFFHKKLRGMPSGPEV-PC-------------------------------------NRD 147
            ..:.::|:|.|||..||  |.| |.                                     ||:
Yeast   224 MAKRIQKYFEKKLSAMP--PRVLPASALKKTSRNRKKNEDMDSPLVIRRSVSTTNDNIGESGNRE 286

  Fly   148 PKAVGRPR----------------TNAPSSAQTERK---CRELLKKLQSITNQTDAMTRNFFSNK 193
            ..:.|||:                .:.|.|...::|   |.::||.|.|..|
Yeast   287 GVSGGRPKRTIHPPKSKDLFDIYENSKPKSKTLQKKFRTCLKILKVLMSKKN------------- 338

  Fly   194 WDSLQKKVDRQYFKSVNEFCLHVDGCFRKYHEPAKILYERVFNQPAAWCTSMNGNSSLESALNAA 258
                 ..::..:.:.|:...|::...|.....|..:  ..:.|....|     ...:::..::
Yeast   339 -----SDINFPFLQPVDPIALNLPNYFDVVKNPMDL--GTISNNLMNW-----KYKTIDQFVD-- 389

  Fly   259 DLNELLAAAKLTVNSLMQCVQMPGSGEPL--TAKSLVETFCDTLNKMINKMEAGQRNSPNPSSSK 321
            |||.:          ...|.|....|..:  ..|.|.|.|                   |....:
Yeast   390 DLNLV----------FYNCFQFNPEGNEVHSMGKKLKELF-------------------NFHWLE 425

  Fly   322 RQKMSPEQETDLVQGEFKPAMELLSGNEIDNLMAVSIESSDDEAIDASMRITDADRCATQKLFAK 386
            .|.:..|.|||             |..|.||..  |..|||||..|..:...|....|.|.|..|
Yeast   426 NQDILNEIETD-------------SDLEEDNYS--SSYSSDDEYDDEDINENDITNPAIQYLEQK 475

  Fly   387 LPTNAMKEIIHMVQQIEGFSSENCGDLSFDVKGLATDTMIMMKSAVTKATRAHSKL---KLKDMQ 448
            |     |::...:||::   .:....||.:.|.......::.:.|:..:.....|.   |:.::.
Yeast   476 L-----KKMEVELQQLK---RQELSKLSKERKRKHLGKTLLRRKAMKHSVDDLKKSITDKINELS 532

  Fly   449 PSEKEGLQRALQSQL----------------------VNITRMLNKNRRRCGPLINFRNKNNTAN 491
            ..|..|:.|.:::.|                      ..|.|:..:         .|..|||  |
Yeast   533 DLEMNGMIRIIKNSLPADEILTSNEDEIEIDLDILDEATIARIYER---------YFEKKNN--N 586

  Fly   492 NVVRK----RATAPLTAK---LKPLQANVMAPQLGAGVVETHNLSDTSDD 534
            |..||    .:|||...|   ||.|:.:        .::..:|.||:.:|
Yeast   587 NSKRKLSGNYSTAPTNKKKKTLKFLEKD--------EIINNNNYSDSEED 628

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	35/115 (30%)
BDF2	NP_010213.1	COG5076	55..378	CDD:227408	69/305 (23%)
		Bromodomain	<344..419	CDD:413371	15/93 (16%)
		Lebercilin	<472..>537	CDD:406132	13/72 (18%)
		BET	521..576	CDD:407211	8/54 (15%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860