Protein Alignment tbrd-2 and BDF1

DIOPT Version :9

• Sequence 1: NP_611401.2
• Gene: tbrd-2 / 37207
• FlyBaseID: FBgn0034423
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: NP_013503.1
• Gene: BDF1 / 851115
• SGDID: S000004391
• Length: 686
• Species: Saccharomyces cerevisiae
• Alignment Length: 624
• Identity: 115/624 - (18%)
• Similarity: 220/624 - (35%)
• Gaps: 163/624 - (26%)

  Fly    11 LKLPNRVQPEFIPHPGMAGRYTNKL-HYFKKHLL---DEARKKKYALDFLEPVDTEALMVPTYYT 71
            :::|....|...|.|.|.....|.: .:.:||.|   ...::.|.|..||:|||...|.:|.|:.
Yeast   125 MEVPKEPAPAPPPEPDMNNLPQNPIPKHQQKHALLAIKAVKRLKDARPFLQPVDPVKLDIPFYFN 189

  Fly    72 VIHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYRKGQMLEKFFHKKLRGM 136
            .|.||||:.||.:::....|:...:...||..:::|...||.....:.:..:.::..|.|.:..|
Yeast   190 YIKRPMDLSTIERKLNVGAYEVPEQITEDFNLMVNNSIKFNGPNAGISQMARNIQASFEKHMLNM 254

  Fly   137 PS---------GPEVPCNRDPKAV--------GRPR---------------TNAPSS---AQTER 166
            |:         |.......|...|        |||:               :..|.|   .|..:
Yeast   255 PAKDAPPVIAKGRRSSAQEDAPIVIRRAQTHNGRPKRTIHPPKSKDIYPYESKKPKSKRLQQAMK 319

  Fly   167 KCRELLKKLQS---------ITNQTDAMTRN------FFSNKWD--SLQKKVDRQYFKSVNEFCL 214
            .|:.:||:|.:         .....|.::.|      :.....|  ::.||::...::::.:|..
Yeast   320 FCQSVLKELMAKKHASYNYPFLEPVDPVSMNLPTYFDYVKEPMDLGTIAKKLNDWQYQTMEDFER 384

  Fly   215 HVDGCFRK---YHEPAKIL------YERVFNQPAAWCTSMN-------------GN-SSLESALN 256
            .|...|:.   ::....|:      .|.|||  :.|....|             |: ...||..:
Yeast   385 DVRLVFKNCYTFNPDGTIVNMMGHRLEEVFN--SKWADRPNLDDYDSDEDSRTQGDYDDYESEYS 447

  Fly   257 AADLNELLAAAKLTVNSLMQCVQMPGSGEPLTAKSLVETFCDTL---------NKMINKMEAGQR 312
            .:|::|     .:..|..:|.::...:...:..:.|.:...:.:         :|...|...|:.
Yeast   448 ESDIDE-----TIITNPAIQYLEEQLARMKVELQQLKKQELEKIRKERRLARGSKKRGKRSKGRS 507

  Fly   313 NSPNPSSSKRQKMSPEQETDLVQGEFKPAMELLSGNEIDNLMAVSIESSDDEAIDASMRITDADR 377
            .|.|.||..|:....:.:|.:..                                      |..|
Yeast   508 GSKNASSKGRRDKKNKLKTVVTY--------------------------------------DMKR 534

  Fly   378 CATQKLFAKLPTNAMKEIIHMVQQIEGFSSENCGDLSFDVKGLATDTMIMMKSAVTKATRAHSKL 442
            ..|::: ..|||:.::..|.::::.....||: .::..|:..|...|::.:.:...:
Yeast   535 IITERI-NDLPTSKLERAIDIIKKSMPNISED-DEVELDLDTLDNHTILTLYNTFFR-------- 589

  Fly   443 KLKDMQPSEKEGLQRALQSQLVNITRMLNK-------NRRRCGPLINFRNKNNTANNVVRKRATA 500
                 |.....|....|.. ...:||..:.       :|:|....::...::.....:..|.|
Yeast   590 -----QYESSSGASNGLDG-TSGVTRDASSLSPTSAGSRKRRSKALSQEEQSRQIEKIKNKLA-- 646

  Fly   501 PLTAKLKPLQANVMAPQLGAGVVETHN-LSDTSDDDVSA 538
             :.....||..|....|:.:.   .|| .|.:||||||:
Yeast   647 -ILDSASPLSQNGSPGQIQSA---AHNGFSSSSDDDVSS 681

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	28/105 (27%)
BDF1	NP_013503.1	COG5076	1..373	CDD:227408	54/247 (22%)
		Bromodomain	<339..417	CDD:413371	13/79 (16%)
		PTZ00108	<386..647	CDD:240271	47/324 (15%)
		BET	527..589	CDD:407211	12/101 (12%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	1.860