DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-2 and Brd8

DIOPT Version :9

Sequence 1:	NP_611401.2	Gene:	tbrd-2 / 37207	FlyBaseID:	FBgn0034423	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001348065.1	Gene:	Brd8 / 78656	MGIID:	1925906	Length:	954	Species:	Mus musculus

Alignment Length:	132	Identity:	34/132 - (25%)
Similarity:	57/132 - (43%)	Gaps:	25/132 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 ARKKKYALDFLEPVDTEALMVPTYYTVIHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFL 110
            |...:||..||:||..:  :.|.|::::.||||:.||.|.::|...:|..|...|...:..|..:
Mouse   796 AANHRYANVFLQPVTDD--IAPGYHSIVQRPMDLSTIKKNIENGLIRSTAEFQRDIMLMFQNAVM 858

  Fly   111 FNRSGDVVYRKG--------QMLEKFF--------------HKKLRGMPSGPEVPCN-RDPKAVG 152
            :|.|...||...        :.:::|.              .|.|||..|..:...: :|...:|
Mouse   859 YNSSDHDVYHMAVEMQRDVLEQIQQFLATQLIMQTSESGISAKSLRGRDSTRKQDASEKDSVPMG 923

  Fly   153 RP 154
            .|
Mouse   924 SP 925

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	29/111 (26%)
Brd8	NP_001348065.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	161..273
		Atrophin-1	<176..356	CDD:331285
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	520..547
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	584..745
		Bromo_brd8_like	782..885	CDD:99939	25/90 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	900..922		6/21 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900