Protein Alignment tbrd-2 and Brdt

DIOPT Version :10

• Sequence 1: NP_611401.2
• Gene: tbrd-2 / 37207
• FlyBaseID: FBgn0034423
• Length: 674
• Species: Drosophila melanogaster
• Sequence 2: XP_063129088.1
• Gene: Brdt / 305123
• RGDID: 1306678
• Length: 952
• Species: Rattus norvegicus
• Alignment Length: 845
• Identity: 179/845 - (21%)
• Similarity: 285/845 - (33%)
• Gaps: 351/845 - (41%)

  Fly     8 SVKLKLPNRVQPEFIPHPGMAGRYTNKLHYFKKHLLDEARKKKYALDFLEPVDTEALMVPTYYTV 72
            |.::.:.|...||:| :....||.||:|.:.::.:|....|..::..|.:|||...|.:|.|||:
  Rat     5 SRQMAIVNPPPPEYI-NAKKTGRLTNQLQFLQRVVLKALWKHSFSWPFQQPVDAAKLKLPDYYTI 68

  Fly    73 IHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYRKGQMLEKFFHKKLRGMP 137
            |..|||:.||.||::|.||:..:|.:.||..:.|||:|:|:.||.:....|.|||.|.:||..||
  Rat    69 IETPMDLSTIKKRLENRYYEKASECVGDFNTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMP 133

  Fly   138 SGPEV------------------------------------------------PCN--------- 145
            ...::                                                |.|
  Rat   134 QEEQIVGGKERMKKDIQQKTAVSSAKEQTPSKSAENVFKRQEIPAGFPDVCLSPLNMAQEAPPTC 198

  Fly   146 ------------------------------------RDPKAVGRP------RTNAPSSAQTER-- 166
                                                |:.|....|      ::..|.|.|..|
  Rat   199 DSQTVVQITKGVKRRADTTTPTTSSAKASSESPPPLREAKPANAPVKENTVKSVLPDSQQQHRVL 263

  Fly   167 ----------KCRELLKKLQSITN-----------QTDAM-TRNFF---SNKWD--SLQKKVDRQ 204
                      .|.|:||::.:..:           ..||: ..|::   .|..|  :::.|:|:|
  Rat   264 KTVKVTEQLKHCSEILKEMLAKKHLPYAWPFYNPVDVDALGLHNYYDIVKNPMDLGTIKGKMDKQ 328

  Fly   205 YFKSVNEFCLHVD----GCFRKYHEP-------------------AKILYERVFNQPAAWCTSMN 246
            .:|...||...|.    .|: ||:.|                   |||..|.|.:..|...|:.:
  Rat   329 EYKDACEFAADVRLMFMNCY-KYNPPDHEVVTMARMLQDVFEMHFAKIPDEPVESMRACHLTTNS 392

  Fly   247 GNS-SLESALNA------------------ADLNELLAAAKLTVNSLMQCV-QMPGSGEPLTAKS 291
            ..: |.||:..|                  |.|.|.|.|    |:..:|.: |:|
  Rat   393 AKALSRESSSEASSGDCSSEDSEDERVQRLAKLQEQLNA----VHQQLQVLSQVP---------- 443

  Fly   292 LVETFCDTLNKMINKMEAGQR--------NSPNPSSSKRQKMSPEQETDLVQGEFKPAMELLSGN 348
                    |.|:..|.|..:|        ...||....:|....|:.......:.||.::|   .
  Rat   444 --------LRKLKKKNEKSKRAPKRKKVNRDENPKKKAKQMKQKEKAKSNQPKKKKPLLKL---E 497

  Fly   349 EIDNLMAVSIESSDDEAIDASMRITDADRCATQKLFAKLPTNAMKEIIHMVQQIE-GFSSENCGD 412
            |.||...::.:.....::|.:                |||.:.:..|:|::|..| ...:.|..:
  Rat   498 EEDNAKPMNYDEKRQLSLDIN----------------KLPGDKLGRIVHIIQSREPSLRNSNPDE 546

  Fly   413 LSFDVKGLATDTMIMMKSAV-----TKATRAHSK--LKLKDMQPSEKEGLQRALQSQLVNITRML 470
            :..|.:.|...|:..::..|     .::.:.|:|  ::.|:...|||   :..|:.:|:::...|
  Rat   547 IEIDFETLKASTLRELEKYVLACLRKRSLKPHAKKVVRSKEELHSEK---KLELERRLLDVNNQL 608

  Fly   471 NKNRRRCGPLINFRNKNNTANNVVRKRATAPLTAKLKPLQANVMAPQLGAGVVETHNLSDTSDDD 535
            |     |                 |||.|.      :|.:...:.|
  Rat   609 N-----C-----------------RKRQTK------RPAKVEKLPP------------------- 626

  Fly   536 VSAPVKLSAIGGTPMRNLPINSNPLQMQPIRSPPKLPHVVELQMSSSSSSESEMKSKSGRLSRSR 600
                                        |...||:|
  Rat   627 ----------------------------PPPPPPEL----------------------------- 634

  Fly   601 SRSMSDTKLRPRSNSSASSRSNSSSSSGSNAGSSSGSRSRSSSSSSSSSNNSSESNDSSDVEVVP 665
                       .|.|..|..|:|||||||  ||||.|.|.|.|.||||.::||:|:| |:.|:.|
  Rat   635 -----------ASGSRLSDSSSSSSSSGS--GSSSSSSSSSGSGSSSSDSSSSDSSD-SEPEISP 685

  Fly   666  665
              Rat   686  685

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	40/101 (40%)
Brdt	XP_063129088.1	None