DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-2 and Brdt

DIOPT Version :9

Sequence 1:	NP_611401.2	Gene:	tbrd-2 / 37207	FlyBaseID:	FBgn0034423	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001012031.1	Gene:	Brdt / 305123	RGDID:	1306678	Length:	326	Species:	Rattus norvegicus

Alignment Length:	173	Identity:	62/173 - (35%)
Similarity:	95/173 - (54%)	Gaps:	3/173 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SVKLKLPNRVQPEFIPHPGMAGRYTNKLHYFKKHLLDEARKKKYALDFLEPVDTEALMVPTYYTV 72
            |.::.:.|...||:| :....||.||:|.:.::.:|....|..::..|.:|||...|.:|.|||:
  Rat     5 SRQMAIVNPPPPEYI-NAKKTGRLTNQLQFLQRVVLKALWKHSFSWPFQQPVDAAKLKLPDYYTI 68

  Fly    73 IHRPMDIGTIVKRVQNNYYKSVNEAIADFKQIISNCFLFNRSGDVVYRKGQMLEKFFHKKLRGMP 137
            |..|||:.||.||::|.||:..:|.:.||..:.|||:|:|:.||.:....|.|||.|.:||..||
  Rat    69 IETPMDLSTIKKRLENRYYEKASECVGDFNTMFSNCYLYNKPGDDIVVMAQALEKLFMQKLSQMP 133

  Fly   138 SGPEVPCNRDPKAVGRPRTNAPSSA--QTERKCRELLKKLQSI 178
            ...::...::.......:..|.|||  ||..|..|.:.|.|.|
  Rat   134 QEEQIVGGKERMKKDIQQKTAVSSAKEQTPSKSAENVFKRQEI 176

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	40/101 (40%)
Brdt	NP_001012031.1	Bromo_Brdt_I_like	26..132	CDD:99929	43/105 (41%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	141..168		7/26 (27%)
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:Q58F21	208..219
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	209..257
		Bromodomain	271..>322	CDD:295360
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000