DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-2 and BPTF

DIOPT Version :9

Sequence 1:	NP_611401.2	Gene:	tbrd-2 / 37207	FlyBaseID:	FBgn0034423	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	XP_005257207.1	Gene:	BPTF / 2186	HGNCID:	3581	Length:	3158	Species:	Homo sapiens

Alignment Length:	104	Identity:	42/104 - (40%)
Similarity:	58/104 - (55%)	Gaps:	2/104 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TNKLHYFKKHLLDEARKKKYALDFLEPVDTEALMVPTYYTVIHRPMDIGTIVKRVQNNYYKSVNE 96
            |.|.:...|.:|...:..|.|..||||||...  .|.||.||..|||:.|:.:|||..||:.:.|
Human  3041 TEKDYEGLKRVLRSLQAHKMAWPFLEPVDPND--APDYYGVIKEPMDLATMEERVQRRYYEKLTE 3103

  Fly    97 AIADFKQIISNCFLFNRSGDVVYRKGQMLEKFFHKKLRG 135
            .:||..:|..||..:|.|....|:..::||.||.:||:|
Human  3104 FVADMTKIFDNCRYYNPSDSPFYQCAEVLESFFVQKLKG 3142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941	41/102 (40%)
BPTF	XP_005257207.1	DDT	241..297	CDD:280886
		WHIM1	339..388	CDD:292246
		PHD1_BPTF	392..434	CDD:277034
		Med15	2217..>2598	CDD:255446
		TNG2	2742..2972	CDD:227367
		PHD2_3_BPTF	2923..2969	CDD:277035
		PHD2_3_BPTF	2981..3027	CDD:277035
		Bromo_gcn5_like	3043..3143	CDD:99941	41/102 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900