DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment tbrd-2 and C29F9.5

DIOPT Version :9

Sequence 1:	NP_611401.2	Gene:	tbrd-2 / 37207	FlyBaseID:	FBgn0034423	Length:	674	Species:	Drosophila melanogaster
Sequence 2:	NP_001355379.1	Gene:	C29F9.5 / 183022	WormBaseID:	WBGene00016220	Length:	261	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	46/248 - (18%)
Similarity:	78/248 - (31%)	Gaps:	76/248 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly   214 LHVDGCFRKYHEPAKILYERVFNQPA--AWCTSMNGNSSLESALNAADLNELLAAAKLTVNSLMQ 276
            ||...|.|:   ..||......|:||  |.|...:                 ....|..:..:..
Worm    48 LHAHECVRR---DIKIREAAEKNEPAPHAMCKIQD-----------------CVIMKEVLKHMTS 92

  Fly   277 CVQMPGSGEPLTAKSLVETFCDTLNKMIN------KMEAGQRNSPNPSSSKRQKMSPEQE----- 330
            |.:.|.......|.|  .|......|..|      |....||.:|...::..:...||.:
Worm    93 CKEGPKCNSVHCASS--RTILSHWKKCFNEECPVCKPIIEQRTAPPQDTTPAEPKKPEHDQIWHL 155

  Fly   331 -------TDLVQGEFKPAMELLSGNEIDNLMAVSIESSDDEAIDASMRITDADRCATQKLFAKLP 388
                   ::|::..:|   .::|..:...|....:::..:.:..|.::|.|    ..|||.|
Worm   156 EVPKTYRSELIEKIYK---GIMSNVKPGTLSEAQMDTWKEYSRSAELQIFD----TAQKLEA--- 210

  Fly   389 TNAMKEIIHMVQQ-----IEGF-------------SSENCGDLSFDVKGLATD 423
                  ..||.::     .|||             .||...:....::|.:||
Worm   211 ------YYHMAREKVCRYQEGFPRRQKTEEKDESDGSEKEDEADDRLEGTSTD 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
tbrd-2	NP_611401.2	Bromo_gcn5_like	34..136	CDD:99941
C29F9.5	NP_001355379.1	ZnF_TAZ	40..128	CDD:214717	20/101 (20%)
C29F9.5	NP_001355379.1	KIX	153..223	CDD:280354	13/85 (15%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5076
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900