Protein Alignment cora and CG12075

DIOPT Version :9

• Sequence 1: NP_523791.2
• Gene: cora / 37205
• FlyBaseID: FBgn0010434
• Length: 1698
• Species: Drosophila melanogaster
• Sequence 2: NP_001245582.1
• Gene: CG12075 / 31815
• FlyBaseID: FBgn0030065
• Length: 1006
• Species: Drosophila melanogaster
• Alignment Length: 637
• Identity: 128/637 - (20%)
• Similarity: 208/637 - (32%)
• Gaps: 172/637 - (27%)

  Fly   161 DYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLAMYGVDLHP 225
            ||||:........:......:|.|:|.|       |.|..     |::.|.| ||||.     .|
  Fly   513 DYDAKFNRVMQQEQQQAAVNHQPAKLRD-------TDKYN-----EINRLLN-KKLAH-----EP 559

  Fly   226 AKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFE---QYESTIG 287
            .:|.:.               |.:|..|              |..:....||...   .::.|.|
  Fly   560 TRDRKS---------------RSRLDDN--------------HDDFDDSDPGSESLPLHHQQTQG 595

  Fly   288 FKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGS--TYRYKGRTQAESTNTPVDRTP 350
            ..:.:|:..:.|    .:...|....:    .|.::...:|:  ..||:.| ..|||   .:..|
  Fly   596 PPVHHHQRKENL----TDKQKFMEYTS----KKQQLLKNYGAGEDQRYRQR-YVEST---TEHLP 648

  Fly   351 PKFNRTLSGARLTSRSMDA-----LALAEKEKVARKSSTLDH---RGDRNADGDAHSRSPIKNKK 407
            | |:....|...||....|     .|:.....:.::::...|   ||||:     |.|
  Fly   649 P-FDHPTGGGVTTSTGGSAGHNKYAAVHRGTDLGQRTTERRHDRDRGDRD-----HPR------- 700

  Fly   408 EKDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSN 472
              ||::|.:...::.:|........||...|...:..||..|   :.|.....|.....|.....
  Fly   701 --DAERERRRDHERDREHSRDRNPYREAESLPYIQSMEKMMK---STGMRYAEATPKTRERERER 760

  Fly   473 KSDKSSGRRGVGIFSSGRKSKSGSPSKDGKDK-SGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEA 536
            :.|:....|...:..|.::.:    ..|.||| ...::...|.|...|      |.:...:.|..
  Fly   761 ERDRDRDYREPPVTQSSQRDR----FHDAKDKFRAMEQRPAVNRYPDV------DERDTPHRDPY 815

  Fly   537 ARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQ 601
            ..::.:.|||..|..|.: :::.:.:.....:.|| .|      :|.|..::.:.|:.:..|...
  Fly   816 RSSSRRRRGSVEPPSTYE-QWSEEEEPPVVISEKS-NP------RDLNRSRARSRGEWEPEPPRH 872

  Fly   602 QKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDK---LNRGQLSPKSRAKLLQDPLLSPTTR 663
            .::                         .:..|.:|:   .||.|    ||     ||......|
  Fly   873 LER-------------------------SVRDRERDRDRDYNRDQ----SR-----DPYRHERER 903

  Fly   664 AKLQGSAVDAAAVPLSDSQKRSY---SPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNKEPGY 725
            .:..|.|           ..|.:   ..||.|....||. |..:....|.|..::|.......|.
  Fly   904 ERPGGRA-----------HSREFLQSVETKNPSTTGSGR-GHMERYPSPAATPIQSVDVGGSGGG 956

  Fly   726 VGPSKADVAAGLAGAAGSKKPGSP-TKTGKGAPGAAA----AAAAGAAGAAA 772
            .|      ..|.:||:.....|.| |:..||...:.|    |...|..|.||
  Fly   957 GG------GGGGSGASSGGNSGKPLTQMAKGYRHSYAEPVFARTGGRVGLAA 1002

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cora	NP_523791.2	B41	34..224	CDD:214604	17/62 (27%)
		FERM_N	36..98	CDD:286467
		FERM_M	116..224	CDD:278785	17/62 (27%)
		FERM_C_4_1_family	219..312	CDD:270005	13/95 (14%)
		FA	323..363	CDD:285894	11/41 (27%)
		PQQ_2	829..>972	CDD:290097
		4_1_CTD	1612..1698	CDD:283537
CG12075	NP_001245582.1	PTB	12..120	CDD:269911

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3530
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900