Protein Alignment cora and Frmd5

DIOPT Version :10

• Sequence 1: NP_523791.2
• Gene: cora / 37205
• FlyBaseID: FBgn0010434
• Length: 1698
• Species: Drosophila melanogaster
• Sequence 2: XP_011237768.1
• Gene: Frmd5 / 228564
• MGIID: 2442557
• Length: 599
• Species: Mus musculus
• Alignment Length: 528
• Identity: 154/528 - (29%)
• Similarity: 238/528 - (45%)
• Gaps: 89/528 - (16%)

  Fly    24 SSSSHGKPALARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLD 88
            ||.|..:.....|.|||.|....:|.|.|.|:.:.:.:|..|||:||||||:.:..|...|.||:
Mouse     9 SSRSLEREYSCTVRLLDDSEYTCTIQRDAKGQYLFDLLCHHLNLLEKDYFGIRFVDPDKQRHWLE 73

  Fly    89 LEKPVSKFFRTDTWPLT--FAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLG 151
            ..|.|.|..|:.. |.|  |.|||||.:|:.|||:||||.:.||::.|:..|||.|.....|||.
Mouse    74 FTKSVVKQLRSQP-PFTMCFRVKFYPADPAALKEEITRYLVFLQIKRDLYHGRLLCKTSDAALLA 137

  Fly   152 SYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTH-KGQSPAEAELHYLENAKK 215
            :|::|:|:||||..:.| ..|...|:..|..:.:||.|:.::|||. .||:||.:||::|..|:.
Mouse   138 AYILQAEIGDYDPGKHP-EGYSSKFQFFPKHSEKLEKKIAEIHKTELSGQTPATSELNFLRKAQT 201

  Fly   216 LAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRIN--------------------------- 253
            |..||||.||.||..|....|.....|.:|.:...|::
Mouse   202 LETYGVDPHPCKDVSGNAAFLAFTPFGFVVLQGNKRVHFIKCILFASFTAAIHWAGGFKDFSTIT 266

  Fly   254 --RFAWPKILKISYKRHHFYIKIRPGEFEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRL---M 313
              ..:|.::.|:.::...||:.:  .:.|:.:..:.:......|.|.|||..:|:..|::|   .
Mouse   267 PKPLSWNEVTKLKFEGKTFYLYV--SQKEEKKIILTYFAPTPEACKHLWKCGIENQAFYKLEKSS 329

  Fly   314 TPEPVSKSKMFPVFGSTYRYKGRTQAE--STNTPVDRTPPKFNRT-----------LSGARLTS- 364
            ....||.|.:| ..||.:||.||...|  .::..:.|.||:.:|.           ..|.||:|
Mouse   330 QVRTVSSSNLF-FKGSRFRYSGRVAKEVMESSAKIKREPPEIHRAGMVPSRSCPSITHGPRLSSV 393

  Fly   365 -------------RSMDALALAEKEKVARKSSTLDHRGD------RNADGDAHSR-SPIKNKKEK 409
                         ..:::|..:......|.||    .||      |::..|::.| :.|.::...
Mouse   394 PRTRRRAVHISIMEGLESLRDSAHSTPVRSSS----HGDTFLPHVRSSRADSNERVAVIADEAYS 454

  Fly   410 DADKEAKLREKKQKEKEEKERKEREKR----ELEEKKKAEKAAKAALAAGAAAG-----AAVNGN 465
            .||  :.|.....:...|.....|:..    .:||:|::|.:...|..|.|..|     ...:|.
Mouse   455 PAD--SVLPTPVAEHSLELMLLSRQINGATCSIEEEKESEASTPTATEAEALGGELRALCQGHGG 517

  Fly   466 DELNDSNK 473
            .|....||
Mouse   518 SEQEQVNK 525

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cora	NP_523791.2	B41	34..224	CDD:214604	83/192 (43%)
		FERM_C_4_1_family	219..312	CDD:270005	25/121 (21%)
		FA	324..364	CDD:462582	15/52 (29%)
		4_1_CTD	1613..1698	CDD:461774
Frmd5	XP_011237768.1	B41	19..210	CDD:214604	83/192 (43%)
		PH-like	191..324	CDD:473070	30/134 (22%)
		FA	338..383	CDD:462582	12/45 (27%)