DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cora and M88.4

DIOPT Version :9

Sequence 1:	NP_523791.2	Gene:	cora / 37205	FlyBaseID:	FBgn0010434	Length:	1698	Species:	Drosophila melanogaster
Sequence 2:	NP_497922.2	Gene:	M88.4 / 175594	WormBaseID:	WBGene00010907	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	241	Identity:	48/241 - (19%)
Similarity:	86/241 - (35%)	Gaps:	58/241 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   498 SKDGKDKSGKDKDKEVGRLGLVV--TSGLGDNQQDQNLDEAARNAAKNR--GSTTPGVTRQYEYA 558
            |:....:|..|.:..:...||:|  .:...:...:||.....|:.:::|  ..:|.|.
Worm   144 SRPDVQRSINDLEHRLFLSGLLVPRNNNNSEGSVNQNALRPQRSCSQSRSVSRSTAGF------- 201

  Fly   559 VDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADG-QEQLSPTSQQKKIGLAFNYAPGNENALKET 622
               |..:||           .::|..||.:..|. ..:|:||..::.:....|...|..
Worm   202 ---DERSSP-----------LERDQRSRTTDIDAPPRRLAPTISRRVVDELKNKIIGES------ 246

  Fly   623 AEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPTTRAKLQGSAV------------DAAA 675
                :.|.:|...:..|||  ...:.||.|.:.|:.:.::|.::.|..:            |.||
Worm   247 ----RIGNMSRSRESSLNR--YESEKRASLSELPIETDSSRYRMFGDTMLRDTKNKSRSLDDLAA 305

  Fly   676 VPLSDSQKRSYSPTKGPQGYSSGAPGSYKPISDPTADFLESQRYNK 721
            .||..:..|.......|       |..: |.|:..||......|.:
Worm   306 DPLVSTNLRGSDLAPPP-------PRRF-PRSEYVADPFGHNSYER 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cora	NP_523791.2	B41	34..224	CDD:214604
		FERM_N	36..98	CDD:286467
		FERM_M	116..224	CDD:278785
		FERM_C_4_1_family	219..312	CDD:270005
		FA	323..363	CDD:285894
		PQQ_2	829..>972	CDD:290097
		4_1_CTD	1612..1698	CDD:283537
M88.4	NP_497922.2	PTB	13..152	CDD:214675	1/7 (14%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3530
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900