Protein Alignment cora and epb41l4b

DIOPT Version :10

• Sequence 1: NP_523791.2
• Gene: cora / 37205
• FlyBaseID: FBgn0010434
• Length: 1698
• Species: Drosophila melanogaster
• Sequence 2: XP_005158090.1
• Gene: epb41l4b / 100332627
• ZFINID: ZDB-GENE-100921-92
• Length: 729
• Species: Danio rerio
• Alignment Length: 703
• Identity: 187/703 - (26%)
• Similarity: 299/703 - (42%)
• Gaps: 133/703 - (18%)

  Fly    25 SSSHGKPAL-ARVTLLDGSLLDVSIDRKAIGRDVINSICAGLNLIEKDYFGLTYETPTDPRTWLD 88
            ::.:.|.|: .||.|||||.::|.:.:.|.|:|:.:.|...|:|:|.|||||.:..|.....|||
Zfish    60 AAGNSKDAITCRVLLLDGSDVNVELPKHAKGQDLFDQIMYHLDLVEADYFGLQFMDPEQVAHWLD 124

  Fly    89 LEKPVSKFFR-TDTWPLTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPCTFVTHALLGS 152
            ..||:.|..| ...:.|.|.||||..||:.|.|:.|||...||:|.|||.|:|.|.:.....||:
Zfish   125 AAKPIKKQIRHGPPYRLFFRVKFYSSEPNNLHEEFTRYLFVLQLRQDILSGKLKCPYDVSVELGA 189

  Fly   153 YLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHKTHKGQSPAEAELHYLENAKKLA 217
            |.:|||:||.|..| .:...:.:|:.:|.||..:|..:.......:|..|::|||::|...|.|.
Zfish   190 YCLQSELGDCDPLE-HSILLVSEFRFSPKQTEIMEADIYRKWVECRGMIPSQAELNFLNKCKWLE 253

  Fly   218 MYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGEFE-- 280
            |||||:|..|..:|.:..||:..:|:||:....:|..|.||||.::.:||:...:.:...:.:
Zfish   254 MYGVDMHFVKGRDGGEYALGLTPTGILVFEGSSKIGLFFWPKITRLDFKRNRLTLVVVEDDEKGR 318

  Fly   281 QYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKM-FPVFGSTYRYKGRTQAESTNT 344
            :.|.|..|:|::....|.|||..||.|.||||..|.....|:. |...||.:|:.|||:.::|::
Zfish   319 EQEHTFVFQLSSSHECKHLWKCAVESHAFFRLRQPTHNKTSRSDFTRLGSRFRFSGRTEYQATHS 383

  Fly   345 PVDRTPPKFNRTLSGARLTSRS---MDALALAEKEKVARKS----STLDHRGDRNADGDAHSRS- 401
            ...|....|.|..| .|..||:   :.|:..|:...::.::    |...::.:.....|...||
Zfish   384 GKVRRASTFERRPS-KRYPSRAQSMVKAMTPAKHPHLSAQTSPEPSLKPYKHNIPIAQDPWQRSH 447

  Fly   402 -------------------------PIK-------NKKEKDADKEAKLREKKQKEKEEKER---- 430
                                     |:.       :.:|.:|....|:.........||:.
Zfish   448 PPPSLTSPLYIQPMELGHTPPPHSFPLSAADTRRFSVEENEAPHSGKIHRCYHHHGYEKQEPLCL 512

  Fly   431 --------------KEREKRELEEKKKAEKAAKAALAAGAAAGAAVNGNDELNDSNKSDKSSG-- 479
                          .:...|.|:.:.:||.||..||...      ::..:|...|.||..||.
Zfish   513 TTAKPKAWVVSPALSDELDRALQNQLEAEPAAWPALHIN------IDMAEEKPLSEKSLPSSPAV 571

  Fly   480 -RRGVGIFSSGRKSKSGSPSKDGKDKSGKDKDKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKN 543
             :..:....|.|.::|.|.:..|...||...|:            ...:.||..  .::.|..|.
Zfish   572 LQEQLKSNISKRATQSDSGNSKGNSSSGDQTDR------------YPSSSQDSG--SSSLNIEKP 622

  Fly   544 RGSTTPGVTRQYEYAVDNDGNTSPTRKSYTPGGFRYDQDPNSRKSGADGQEQLSPTSQQKKIGLA 608
            |......:.||:.:      |.|             |:|        |..|.|:..|.|..:|
Zfish   623 RVDRRKRLVRQFSF------NHS-------------DED--------DLPEALAAISSQCSMG-- 658

  Fly   609 FNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLSPT 661
                   :::...:.:|.....:.|..:|         .||.:....||..|:
Zfish   659 -------KSSSNSSLDKQVQPPIYPPQKD---------TSRLEHDSSPLFFPS 695

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cora	NP_523791.2	B41	34..224	CDD:214604	78/190 (41%)
		FERM_C_4_1_family	219..312	CDD:270005	33/94 (35%)
		FA	324..364	CDD:462582	13/39 (33%)
		4_1_CTD	1613..1698	CDD:461774
epb41l4b	XP_005158090.1	B41	69..260	CDD:214604	78/191 (41%)
		FERM_C_NBL4_NBL5	256..349	CDD:270007	31/92 (34%)
		FA	362..403	CDD:462582	13/41 (32%)