Protein Alignment hppy and SSK2

DIOPT Version :10

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_014428.1
• Gene: SSK2 / 855765
• SGDID: S000005314
• Length: 1579
• Species: Saccharomyces cerevisiae
• Alignment Length: 309
• Identity: 96/309 - (31%)
• Similarity: 149/309 - (48%)
• Gaps: 43/309 - (13%)

  Fly    13 LSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQ----IIQQEII 73
            |:|.||  |....::....||.||:|.||.|..:.:.|:.|:|.|.::.|..:|    :|::|:.
Yeast  1255 LASSIS--NVSMRWQKRNFIGGGTFGRVYSAVDLDNGEILAVKEINIQDSKSMQKIFPLIKEEMS 1317

  Fly    74 MMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLH 138
            ::....||||::|||..:.|||:.|.||:|.||||..:.:......|:.......:.|:||.|||
Yeast  1318 VLEILNHPNIVSYYGVEVHRDKVNIFMEYCEGGSLAALLEHGRIEDEMVTQVYTLQLLEGLAYLH 1382

  Fly   139 SMGKMHRDIKGANILLTEYGDVKLADFGVSAQIT------ATINKRKS----------------- 180
            ..|.:|||:|..||||...|.:|..|||.:.:|.      |::||.::
Yeast  1383 ESGIVHRDVKPENILLDFNGVIKYVDFGAAKKIANNGTRLASMNKIENADGEHEDVTHVSDSKAV 1447

  Fly   181 ---------FIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLM 236
                     .:|||.:||||........|.....|:|:.|...:|:...:.|..:|....|:...
Yeast  1448 KNNENALLDMMGTPMYMAPESITGSTTKGKLGADDVWSLGCVVLEMITGRRPWANLDNEWAIMYH 1512

  Fly   237 SKSGFKP--PTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHPFV 283
            ..:|..|  ||   ||:.|.....|::..|.:||.||.:|..||..|::
Yeast  1513 VAAGHTPQFPT---KDEVSSAGMKFLERCLIQNPSKRASAVELLMDPWI 1558

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	91/295 (31%)
		CNH	864..1193	CDD:470577
SSK2	NP_014428.1	STKc_MEKK4	1265..1558	CDD:270796	91/295 (31%)