Protein Alignment hppy and SIK1

DIOPT Version :9

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_564955.1
• Gene: SIK1 / 843253
• AraportID: AT1G69220
• Length: 836
• Species: Arabidopsis thaliana
• Alignment Length: 671
• Identity: 210/671 - (31%)
• Similarity: 301/671 - (44%)
• Gaps: 137/671 - (20%)

  Fly     1 MAAAHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKL-EPSDD 64
            |...:|..:...|...|:|.:|..:||.:.::|.|:||.||||:.::::|:.|:|||.| |..:.
plant   224 MQQQNSKMSTTSLPDSITREDPTTKYEFLNELGKGSYGSVYKARDLKTSEIVAVKVISLTEGEEG 288

  Fly    65 IQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVT-GPLTEVQIAYMCR 128
            .:.|:.||.|::.|.|||::.|.|||...|.|||.||:|||||:.|:..|| ..|.|.||||:||
plant   289 YEEIRGEIEMLQQCNHPNVVRYLGSYQGEDYLWIVMEYCGGGSVADLMNVTEEALEEYQIAYICR 353

  Fly   129 ETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVA 193
            |.||||.||||:.|:||||||.||||||.|:|||.||||:||:|.|::||.:|||||:||||||.
plant   354 EALKGLAYLHSIYKVHRDIKGGNILLTEQGEVKLGDFGVAAQLTRTMSKRNTFIGTPHWMAPEVI 418

  Fly   194 AVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKP-PTLNNKDKWSPTFH 257
            ...|   |:...|:||.|::|||:||..||...:||||.||::|   .:| |.|.:|:|||..||
plant   419 QENR---YDGKVDVWALGVSAIEMAEGLPPRSSVHPMRVLFMIS---IEPAPMLEDKEKWSLVFH 477

  Fly   258 NFIKTALTKNPKKRPTAERLLQHPFVQ-CEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVP 321
            :|:...|||.|:.||||..:|:|.||: |:.........::|
plant   478 DFVAKCLTKEPRLRPTAAEMLKHKFVERCKTGASAMSPKIEK----------------------- 519

  Fly   322 QRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRA-TLPLN 385
                |:....|..:.||: .:...:...||...:||                |||.:.. :.|..
plant   520 ----SRQIRATMALQAQS-VVAPSLEDTSTLGPKSS----------------EELGITVPSKPPQ 563

  Fly   386 NDTKDPLGAECSCSSHNGGA--AGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQH 448
            |.|:.||.:..:.....|..  ||.||..|..:..|......|.|.|     .....:.....|.
plant   564 NSTEAPLTSTLNRQHITGNTVLAGEGGDFGTMIVHGEDETEESDSRS-----QLVREKESSSSQF 623

  Fly   449 HHHPNH----------LHQHQ---SHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANN 500
            ...|..          :|..:   :..||.:........|...|.|.             ...:|
plant   624 EGVPREFPGEELPDSWIHDKKKPPAIDLPVEASISQSMQASSSHEHR-------------TKLHN 675

  Fly   501 ISSSASLASMPGLSAYLG--MRSHVVGHMGMGF----------GMGLGMSNLRTTSIDADDDELV 553
            |:.:    .|.|.|...|  :::..||......          |..:.:..||.|.|
plant   676 IAGT----QMEGGSDASGSTLKNETVGRKAFALQDKLWSIYAAGNTVPIPFLRATDI-------- 728

  Fly   554 AADVAMNNAAAAVPGNGSGAGNGSGSGCSA-SAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNS 617
                   :..|.:..|..|.....|:|..| .|...|..||:.:|                 ...
plant   729 -------SPIALLSENMIGGMQQDGNGTVAVEALQELFTSSDPQS-----------------KKG 769

  Fly   618 NNGHGHAPITSSISSSASSAS 638
            ..|....|:..|:....:::|
plant   770 RRGQNEMPLPPSVYQRLTTSS 790

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	138/260 (53%)
		S_TKc	26..283	CDD:214567	138/259 (53%)
		CNH	869..1184	CDD:279162
SIK1	NP_564955.1	STKc_MAP4K3_like	248..503	CDD:270788	138/260 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	282	1.000	Domainoid score	I389
eggNOG	1	0.900	-	-		E1_KOG0576
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X579
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810