DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment hppy and YDA

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_001319310.1	Gene:	YDA / 842674	AraportID:	AT1G63700	Length:	883	Species:	Arabidopsis thaliana

Alignment Length:	539	Identity:	153/539 - (28%)
Similarity:	233/539 - (43%)	Gaps:	105/539 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDD------IQIIQQEIIMMRDCR 79
            :|...::..:.:|.|::|.||.....:|.|:.|:|.:.| .|||      .|.:.|||.::...|
plant   395 SPGSRWKKGRLLGMGSFGHVYLGFNSESGEMCAMKEVTL-CSDDPKSRESAQQLGQEISVLSRLR 458

  Fly    80 HPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMH 144
            |.||:.||||....|||:|.:|:..|||:..:.|..|...|..|....::.|.||.|||:...:|
plant   459 HQNIVQYYGSETVDDKLYIYLEYVSGGSIYKLLQEYGQFGENAIRNYTQQILSGLAYLHAKNTVH 523

  Fly   145 RDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWA 209
            |||||||||:..:|.||:||||::..|||. :...||.|:||||||||  ::...|.|...|||:
plant   524 RDIKGANILVDPHGRVKVADFGMAKHITAQ-SGPLSFKGSPYWMAPEV--IKNSNGSNLAVDIWS 585

  Fly   210 CGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTA 274
            .|.|.:|:|..:||......:.|:|.:..|...|   :..|..|....:|::..|.:||..||||
plant   586 LGCTVLEMATTKPPWSQYEGVPAMFKIGNSKELP---DIPDHLSEEGKDFVRKCLQRNPANRPTA 647

  Fly   275 ERLLQHPFVQCEM-------------SLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRIAS 326
            .:||.|.||:..|             ::.||...::.....:.:....||.::
plant   648 AQLLDHAFVRNVMPMERPIVSGEPAEAMNVASSTMRSLDIGHARSLPCLDSED------------ 700

  Fly   327 KMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTKDP 391
                      |.|:..| |:...|.:: .|.||..:...:|                       |
plant   701 ----------ATNYQQK-GLKHGSGFS-ISQSPRNMSCPIS-----------------------P 730

  Fly   392 LGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSS---SSSGGATVGTTHHQHQQHHQHHHHPN 453
            :|:.. ..||:...:|......:   :...|.:|||   :..|||.        ..|||.....|
plant   731 VGSPI-FHSHSPHISGRRSPSPI---SSPHALSGSSTPLTGCGGAI--------PFHHQRQTTVN 783

  Fly   454 HLHQ----------------HQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNIS 502
            .||:                :...|.|.:||.:|..:.:...|.......||..| ...|.:|..
plant   784 FLHEGIGSSRSPGSGGNFYTNSFFQEPSRQQDRSRSSPRTPPHVFWDNNGSIQPG-YNWNKDNQP 847

  Fly   503 SSASLASMPGLSAYLGMRS 521
            ..:...|...||.:|.::|
plant   848 VLSDHVSQQLLSEHLKLKS 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	102/263 (39%)
		S_TKc	26..283	CDD:214567	102/262 (39%)
		CNH	869..1184	CDD:279162
YDA	NP_001319310.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910