DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and NP1

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_563832.2	Gene:	NP1 / 837421	AraportID:	AT1G09000	Length:	666	Species:	Arabidopsis thaliana

Alignment Length:	421	Identity:	124/421 - (29%)
Similarity:	189/421 - (44%)	Gaps:	65/421 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 QKIGSGTYGDVYKAKRIQSNELAAIKVI--------KLEPSDDIQIIQQEIIMMRDCRHPNIIAY 86
            |.||.|.:|.||....:.|.||.|:|.:        |.:....||.:::|:.::::..||||:.|
plant    73 QLIGRGAFGTVYMGMNLDSGELLAVKQVLIAANFASKEKTQAHIQELEEEVKLLKNLSHPNIVRY 137

  Fly    87 YGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGAN 151
            .|:....|.|.|.:||..|||:..:.:..||..|..:....|:.|.||||||:...|||||||||
plant   138 LGTVREDDTLNILLEFVPGGSISSLLEKFGPFPESVVRTYTRQLLLGLEYLHNHAIMHRDIKGAN 202

  Fly   152 ILLTEYGDVKLADFGVSAQIT--ATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITA 214
            ||:...|.:||||||.|.|:.  ||:...||..||||||||||..   :.|::...|||:.|.|.
plant   203 ILVDNKGCIKLADFGASKQVAELATMTGAKSMKGTPYWMAPEVIL---QTGHSFSADIWSVGCTV 264

  Fly   215 IELAELQPPMFDLH-PMRALFLMSKSGFKPP---TLNNKDKWSPTFHNFIKTALTKNPKKRPTAE 275
            ||:...:.|....: .:.|:|.:..:...||   ||::..|      :|:...|.:.|..||||.
plant   265 IEMVTGKAPWSQQYKEVAAIFFIGTTKSHPPIPDTLSSDAK------DFLLKCLQEVPNLRPTAS 323

  Fly   276 RLLQHPFVQCEMSLRVAKEL---LQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRTNGVPA 337
            .||:||||..:.....:.:|   |....:|.|.       ...:....|......:....| ..:
plant   324 ELLKHPFVMGKHKESASTDLGSVLNNLSTPLPL-------QINNTKSTPDSTCDDVGDMCN-FGS 380

  Fly   338 QNHTL---KTGMTTNSTWNERSSSPE---------------------TLPSDMSLLQYIDEELKL 378
            .|::|   ...:...:.|.:..:..:                     ||..|..|.:..|:...:
plant   381 LNYSLVDPVKSIQNKNLWQQNDNGGDEDDMCLIDDENFLTFDGEMSSTLEKDCHLKKSCDDISDM 445

  Fly   379 RATL-------PLNNDTKDPLGAECSCSSHN 402
            ...|       |.|.:.:..:..||...|::
plant   446 SIALKSKFDESPGNGEKESTMSMECDQPSYS 476

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	102/266 (38%)
		S_TKc	26..283	CDD:214567	102/266 (38%)
		CNH	869..1184	CDD:279162
NP1	NP_563832.2	STKc_MAPKKK	68..331	CDD:270783	102/266 (38%)
NP1	NP_563832.2	S_TKc	69..331	CDD:214567	102/266 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910