DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and AT4G10730

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_192811.4	Gene:	AT4G10730 / 826667	AraportID:	AT4G10730	Length:	711	Species:	Arabidopsis thaliana

Alignment Length:	866	Identity:	205/866 - (23%)
Similarity:	315/866 - (36%)	Gaps:	284/866 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 NPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEP-SDDIQIIQQEIIMMRDCRHPNII 84
            ||:| |:|::::|.|....|::|..:.:||:.|||.:.|:. :.::..|::|...|....|||:|
plant    43 NPKD-YKLMEEVGYGASAVVHRAIYLPTNEVVAIKSLDLDRCNSNLDDIRREAQTMTLIDHPNVI 106

  Fly    85 AYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGP--LTEVQIAYMCRETLKGLEYLHSMGKMHRDI 147
            ..:.|:.....||:.|.|...||...:.:...|  ..|..|..|.:||||.|:|||..|.:|||:
plant   107 KSFCSFAVDHHLWVVMPFMAQGSCLHLMKAAYPDGFEEAAICSMLKETLKALDYLHRQGHIHRDV 171

  Fly   148 KGANILLTEYGDVKLADFGVSAQITATINK---RKSFIGTPYWMAPEVAAVERKGGYNQLCDIWA 209
            |..||||.:.|::||.||||||.:....::   |.:|:|||.||||||  ::...|||...|||:
plant   172 KAGNILLDDTGEIKLGDFGVSACLFDNGDRQRARNTFVGTPCWMAPEV--LQPGSGYNSKADIWS 234

  Fly   210 CGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLN-NKD-KWSPTFHNFIKTALTKNPKKRP 272
            .||||:|||....|.....||:.|.:..::.  ||.|: ::| |:|.:|...:...|.|:..|||
plant   235 FGITALELAHGHAPFSKYPPMKVLLMTIQNA--PPGLDYDRDKKFSKSFKELVALCLVKDQTKRP 297

  Fly   273 TAERLLQHPFVQ-------CEMSLRV--------AKELLQKYQSPNPQFYYYLDGDEESVAGVPQ 322
            |||:||:|.|.:       |...|.|        .|.|..|            |..:.::.|
plant   298 TAEKLLKHSFFKNVKPPEICVKKLFVDLPPLWTRVKALQAK------------DAAQLALKG--- 347

  Fly   323 RIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNND 387
                 |.|......:|:. .:.|:   |.||                 :..|:||.:|:| |::|
plant   348 -----MASADQDAISQSE-YQRGV---SAWN-----------------FNIEDLKEQASL-LDDD 385

  Fly   388 TKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQH--HQHHH 450
                                                          .:.|...:.::.  .|.|:
plant   386 ----------------------------------------------DILTESREEEESFGEQLHN 404

  Fly   451 HPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNIS----SSASLASMP 511
            ..|...|....||..:......:|:..|      :...|.....|.|:...|    :|:|...:|
plant   405 KVNDRGQVSGSQLLSENMNGKEKASDTE------VVEPICEEKSTLNSTTSSVEQPASSSEQDVP 463

  Fly   512 GLSAYLGMRSHVVGHMG-MGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGN 575
            ...   |....:..|.| :..|:.|
plant   464 QAK---GKPVRLQTHSGPLSSGVVL---------------------------------------- 485

  Fly   576 GSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHAPITSSISSSASSASFY 640
                                               :||:|...:|:..:.....:.||...|..:
plant   486 -----------------------------------INSDSEKVHGYERSESERQLKSSVRRAPSF 515

  Fly   641 NRLLLLDN----SSGDAVVGGNGG--------GSSNISSSGGASSGTNGLLDKHELDALPQAATK 693
            :..|.|.|    :|..|.:..:||        ..:|:....|..|.|:..||......|.::|
plant   516 SGPLNLPNRASANSLSAPIKSSGGFRDSIDDKSKANVVQIKGRFSVTSENLDLARASPLRKSA-- 578

  Fly   694 SAGDGFSHSNSPTANSGAGATGSRDNDGPSSSNSSHL------YQNLLRSSS------------- 739
            |.|:....|..||..:             ...:||||      .|||.:.:|
plant   579 SVGNWILDSKMPTGQA-------------IKESSSHLSFIIPQLQNLFQQNSMQQDLIMNLVNTL 630

  Fly   740 ---GETPAGSSSAGNNCDYRHENNQNG-LEDSPRRHSSMDQLIGLLENMGKSPRTRSLSDGGTQ- 799
               .||..||              ||| |...||...|.    |.:..:..:.|.|.|....|:
plant   631 QQAAETTDGS--------------QNGKLPPLPRGSDSN----GTVVELTAAERERLLLTKITEL 677

  Fly   800 --------DDDEAEKEAQPDL 812
                    ::.|.||..|..|
plant   678 RARMKELTEELEVEKSKQTQL 698

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	102/265 (38%)
		S_TKc	26..283	CDD:214567	102/264 (39%)
		CNH	869..1184	CDD:279162
AT4G10730	NP_192811.4	STKc_OSR1_SPAK	45..308	CDD:270787	103/267 (39%)
AT4G10730	NP_192811.4	S_TKc	47..308	CDD:214567	102/264 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910