DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and NP3

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_187254.1	Gene:	NP3 / 819774	AraportID:	AT3G06030	Length:	651	Species:	Arabidopsis thaliana

Alignment Length:	421	Identity:	131/421 - (31%)
Similarity:	195/421 - (46%)	Gaps:	75/421 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 IGSGTYGDVYKAKRIQSNELAAIKVIKLEPSD--------DIQIIQQEIIMMRDCRHPNIIAYYG 88
            ||.|.:|.||....:.|.||.|||.:.:.||.        .|:.:::|:.::::..||||:.|.|
plant    74 IGCGAFGRVYMGMNLDSGELLAIKQVLIAPSSASKEKTQGHIRELEEEVQLLKNLSHPNIVRYLG 138

  Fly    89 SYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANIL 153
            :....|.|.|.|||..|||:..:.:..|...|..|....::.|.||||||:.|.|||||||||||
plant   139 TVRESDSLNILMEFVPGGSISSLLEKFGSFPEPVIIMYTKQLLLGLEYLHNNGIMHRDIKGANIL 203

  Fly   154 LTEYGDVKLADFGVSAQIT--ATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIE 216
            :...|.::|||||.|.::.  ||:|..||..||||||||||..   :.|::...|||:.|.|.||
plant   204 VDNKGCIRLADFGASKKVVELATVNGAKSMKGTPYWMAPEVIL---QTGHSFSADIWSVGCTVIE 265

  Fly   217 LAELQPPMFDLHPMRALFL-MSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQH 280
            :|..:||..:.:...|..| :.::...||.   .:..||...:|:...|.|.|..|.:|..||||
plant   266 MATGKPPWSEQYQQFAAVLHIGRTKAHPPI---PEDLSPEAKDFLMKCLHKEPSLRLSATELLQH 327

  Fly   281 PFVQ-----------------------------------------------CEM-SLRVAKELLQ 297
            |||.                                               ||: |||  ..::.
plant   328 PFVTGKRQEPYPAYRNSLTECGNPITTQGMNVRSSINSLIRRSTCSGLKDVCELGSLR--SSIIY 390

  Fly   298 KYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRTNGVPAQNHTLKTGMT----TNSTWN-ERSS 357
            ..:|.|..| .:.|||.:.:..........:.|..|.|.:|:..|.....    :...|: :...
plant   391 PQKSNNSGF-GWRDGDSDDLCQTDMDDLCNIESVRNNVLSQSTDLNKSFNPMCDSTDNWSCKFDE 454

  Fly   358 SPETLPSDMSLLQYIDEELKLRATLPLNNDT 388
            ||:.:.|..:||.|  :..:|:..:|.:.:|
plant   455 SPKVMKSKSNLLSY--QASQLQTGVPCDEET 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	103/261 (39%)
		S_TKc	26..283	CDD:214567	103/261 (39%)
		CNH	869..1184	CDD:279162
NP3	NP_187254.1	STKc_MAPKKK	67..330	CDD:270783	103/261 (39%)
NP3	NP_187254.1	S_TKc	68..330	CDD:214567	103/261 (39%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910