Protein Alignment hppy and TAOK1

DIOPT Version :9

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_065842.1
• Gene: TAOK1 / 57551
• HGNCID: 29259
• Length: 1001
• Species: Homo sapiens
• Alignment Length: 522
• Identity: 154/522 - (29%)
• Similarity: 241/522 - (46%)
• Gaps: 111/522 - (21%)

  Fly    19 RRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKL---EPSDDIQIIQQEIIMMRDCRH 80
            :.:|:..:..:::||.|::|.||.|:.:::||:.|||.:..   :.::..|.|.:|:..::..:|
Human    21 KEDPEKLFTDLREIGHGSFGAVYFARDVRTNEVVAIKKMSYSGKQSTEKWQDIIKEVKFLQRIKH 85

  Fly    81 PNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQV-TGPLTEVQIAYMCRETLKGLEYLHSMGKMH 144
            ||.|.|.|.|||....|:.||:| .||..|:.:| ..||.||:||.:....|:||.||||...:|
Human    86 PNSIEYKGCYLREHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALQGLAYLHSHTMIH 149

  Fly   145 RDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWA 209
            ||||..||||||.|.||||||| ||.:.:..|   ||:||||||||||.....:|.|:...|:|:
Human   150 RDIKAGNILLTEPGQVKLADFG-SASMASPAN---SFVGTPYWMAPEVILAMDEGQYDGKVDVWS 210

  Fly   210 CGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTA 274
            .|||.|||||.:||:|:::.|.||:.::::  :.|||.: ::||..|.||:.:.|.|.|:.|||:
Human   211 LGITCIELAERKPPLFNMNAMSALYHIAQN--ESPTLQS-NEWSDYFRNFVDSCLQKIPQDRPTS 272

  Fly   275 ERLLQHPFVQCEMSLRVAKELLQK---------------------YQSPNPQFYYYLDGDEESVA 318
            |.||:|.||..|....|..:|:|:                     .::.|.......:.:||...
Human   273 EELLKHIFVLRERPETVLIDLIQRTKDAVRELDNLQYRKMKKLLFQEAHNGPAVEAQEEEEEQDH 337

  Fly   319 GVPQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPE---------------TLPSDMSL 368
            ||.:      |...|.|.:........::.:|..:..:|.|:               |:.|:.|:
Human   338 GVGR------TGTVNSVGSNQSIPSMSISASSQSSSVNSLPDVSDDKSELDMMEGDHTVMSNSSV 396

  Fly   369 LQYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGA 433
            :....||...|..........||.... ..|.|.
Human   397 IHLKPEEENYREEGDPRTRASDPQSPP-QVSRHK------------------------------- 429

  Fly   434 TVGTTHHQHQQHH-------------QHHHHPNHLHQHQSHQLPQQQQQQSH--------QAAQQ 477
                :|:::::|.             |.|...:.|.:..|.....::|.|..        :|...
Human   430 ----SHYRNREHFATIRTASLVTRQMQEHEQDSELREQMSGYKRMRRQHQKQLMTLENKLKAEMD 490

  Fly   478 EH 479
            ||
Human   491 EH 492

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	115/261 (44%)
		S_TKc	26..283	CDD:214567	115/260 (44%)
		CNH	869..1184	CDD:279162
TAOK1	NP_065842.1	STKc_TAO1	2..318	CDD:270805	122/304 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..433		21/150 (14%)
		SbcC	<442..>877	CDD:223496	9/51 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	567..587
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	911..1001

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910