Protein Alignment hppy and TAOK3

DIOPT Version :9

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001333416.1
• Gene: TAOK3 / 51347
• HGNCID: 18133
• Length: 907
• Species: Homo sapiens
• Alignment Length: 533
• Identity: 165/533 - (30%)
• Similarity: 244/533 - (45%)
• Gaps: 107/533 - (20%)

  Fly    21 NPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKL---EPSDDIQIIQQEIIMMRDCRHPN 82
            :|::.:..:.:||.|::|.||.|....::|:.|||.:..   :..:..|.|.:|:..:|..:|||
Human    19 DPEELFIGLHEIGHGSFGAVYFATNAHTSEVVAIKKMSYSGKQTHEKWQDILKEVKFLRQLKHPN 83

  Fly    83 IIAYYGSYLRRDKLWICMEFCGGGSLQDIYQV-TGPLTEVQIAYMCRETLKGLEYLHSMGKMHRD 146
            .|.|.|.||:....|:.||:| .||..|:.:| ..||.||:||.:....|.||.||||...:|||
Human    84 TIEYKGCYLKEHTAWLVMEYC-LGSASDLLEVHKKPLQEVEIAAITHGALHGLAYLHSHALIHRD 147

  Fly   147 IKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACG 211
            ||..||||||.|.||||||| ||.:.:..|   ||:||||||||||.....:|.|:...|||:.|
Human   148 IKAGNILLTEPGQVKLADFG-SASMASPAN---SFVGTPYWMAPEVILAMDEGQYDGKVDIWSLG 208

  Fly   212 ITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAER 276
            ||.|||||.:||:|:::.|.||:.::::  ..|||.: ::|:.:|..|:...|.|.|::|||:..
Human   209 ITCIELAERKPPLFNMNAMSALYHIAQN--DSPTLQS-NEWTDSFRRFVDYCLQKIPQERPTSAE 270

  Fly   277 LLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRTNGVPAQNHT 341
            ||:|.||:.:..|||..:|:|:.:          |...| :..:..|...|:..:.
Human   271 LLRHDFVRRDRPLRVLIDLIQRTK----------DAVRE-LDNLQYRKMKKILFQE--------- 315

  Fly   342 LKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTKDPLGAECSCSSHNGGAA 406
                 |.|...||.....|......||                 |...|.||:..|..|.:
Human   316 -----TRNGPLNESQEDEEDSEHGTSL-----------------NREMDSLGSNHSIPSMS---- 354

  Fly   407 GGGGGGGVGVGAGGAAANG----------------------SSSSS------GGATVGTTHHQHQ 443
                   |..|:..::.|.                      :||||      |.....|..|...
Human   355 -------VSTGSQSSSVNSMQEVMDESSSELVMMHDDESTINSSSSVVHKKVGFLVPSTEDHVFI 412

  Fly   444 QHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSI-SSGLVTANANNISSSASL 507
            :....|..|.          |:.:..||.| :|..|:.:....::| |:.|||...:.......|
Human   413 RDEAGHGDPR----------PEPRPTQSVQ-SQALHYRNRERFATIKSASLVTRQIHEHEQENEL 466

  Fly   508 ASMPGLSAYLGMR 520
            ...  :|.|..||
Human   467 REQ--MSGYKRMR 477

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	112/261 (43%)
		S_TKc	26..283	CDD:214567	112/260 (43%)
		CNH	869..1184	CDD:279162
TAOK3	NP_001333416.1	STKc_TAO3	2..314	CDD:270803	124/313 (40%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..362		15/73 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	414..434		6/30 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	574..605

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910