Protein Alignment hppy and fray

DIOPT Version :9

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001303449.2
• Gene: fray / 44233
• FlyBaseID: FBgn0023083
• Length: 707
• Species: Drosophila melanogaster
• Alignment Length: 630
• Identity: 175/630 - (27%)
• Similarity: 247/630 - (39%)
• Gaps: 134/630 - (21%)

  Fly    21 NPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEP-SDDIQIIQQEIIMMRDCRHPNII 84
            |.:|:|||...||.|....|:.|..|..||..|||.|.||. :..:..:.:||..|..|.|.|::
  Fly   188 NSKDDYELRDVIGVGATAVVHGAYCIPRNEKCAIKRINLEKWNTSMDELLKEIQAMSSCFHENVV 252

  Fly    85 AYYGSYLRRDKLWICMEFCGGGSLQDIYQ--------VTGPLTEVQIAYMCRETLKGLEYLHSMG 141
            .|:.|::.|::||:.:....||||.||.:        ..|...|..||.:.:|.||||||.||.|
  Fly   253 TYHTSFVVREELWLVLRLLEGGSLLDIIKHKMRTSNCKQGVFDEATIATVLKEVLKGLEYFHSNG 317

  Fly   142 KMHRDIKGANILLTEYGDVKLADFGVSAQITA--TINKRK---SFIGTPYWMAPEVAAVERKGGY 201
            ::|||||..|||:.:.|.:::|||||||.:..  .::::|   :|:|||.||||||  :|:..||
  Fly   318 QIHRDIKAGNILIGDDGTIQIADFGVSAWLATGRDLSRQKVRHTFVGTPCWMAPEV--MEQDHGY 380

  Fly   202 NQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTL----NNKDK---WSPTFHNF 259
            :...|||:.||||||:|....|.....||:.|.|..::  .||||    ::||:   :..||...
  Fly   381 DFKADIWSFGITAIEMATGTAPYHKYPPMKVLMLTLQN--DPPTLDTGADDKDQYKAYGKTFRKM 443

  Fly   260 IKTALTKNPKKRPTAERLLQHPFVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRI 324
            |...|.|.|.|||||..||:|.|.:   ..:..|.|.|......|..               :..
  Fly   444 IVECLQKEPSKRPTASELLKHAFFK---KAKDRKYLTQTLLQSGPSM---------------ETR 490

  Fly   325 ASKMTSRTNGVPAQNHTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLRATLPLNNDTK 389
            ..|...|..|...:.|...||   ...|:.                  :||
  Fly   491 VHKAAKRQPGASGRLHRTVTG---EWVWSS------------------EEE-------------- 520

  Fly   390 DPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQHHQHHHHPNH 454
                       .|||:|.|.|.|                                   ...||:
  Fly   521 -----------DNGGSATGSGTG-----------------------------------DRKHPS- 538

  Fly   455 LHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSGLVTANANNISSSASLASMPGLSAYLGM 519
             ....|...|..:.:::..:..........:|.|:||..||..|...:.:.:...:....|.|.:
  Fly   539 -SDSDSEDRPMNRLERADSSDSDREEPSPEITHSVSSATVTPGAPAAAGAGAAQELTAGIAQLPL 602

  Fly   520 RSHVVGHMGMGFGMGLGMSNLRTTSIDADDDELVAADVAMNNAAAAVPGNGSGAGNGSGSGCSAS 584
            .|...|. .....:.|.|.|||....|...:.:|..|.|...|...|     .||..........
  Fly   603 PSEAAGE-APPVNLVLRMRNLRRELHDIRFEFVVGKDTAEGIATELV-----DAGLVDALDTQPM 661

  Fly   585 AAH--YLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHAPIT 627
            |.|  .|..:|........|.|....|....:..|..|:....||
  Fly   662 ATHLDQLIAASATMKTITFQLSSGVQPGEVPDERSLVGYAQISIT 706

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	113/278 (41%)
		S_TKc	26..283	CDD:214567	113/277 (41%)
		CNH	869..1184	CDD:279162
fray	NP_001303449.2	STKc_OSR1_SPAK	191..467	CDD:270787	114/279 (41%)
		OSR1_C	613..670	CDD:403428	16/61 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438533
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940