DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and stk24b

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	XP_005165890.1	Gene:	stk24b / 406786	ZFINID:	ZDB-GENE-040426-2841	Length:	432	Species:	Danio rerio

Alignment Length:	304	Identity:	139/304 - (45%)
Similarity:	197/304 - (64%)	Gaps:	20/304 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 AHSHHNANMLSSDISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPS-DDIQI 67
            |||....::......:.:|::.:..:::||.|::|:|:|....::.::.|||:|.||.: |:|:.
Zfish     2 AHSPVQGSLPGMQNLKADPEELFTKLERIGKGSFGEVFKGIDNRTQKVVAIKIIDLEEAEDEIED 66

  Fly    68 IQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLK 132
            |||||.::..|..|.:..||||||:..||||.||:.||||..|:.: .|.|.|.|||.:.||.||
Zfish    67 IQQEITVLSQCDSPFVTKYYGSYLKDTKLWIIMEYLGGGSALDLLE-PGSLDETQIATILREILK 130

  Fly   133 GLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVER 197
            |||||||..|:|||||.||:||:|.|:||||||||:.|:|.|..||.:|:|||:||||||.   :
Zfish   131 GLEYLHSEKKIHRDIKAANVLLSEQGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVI---K 192

  Fly   198 KGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKT 262
            :..|:...|||:.||||||||:.:||..|||||:.|||:.|:  .||||  :..:......|::.
Zfish   193 QSAYDSKADIWSLGITAIELAKGEPPHSDLHPMKVLFLIPKN--NPPTL--EGNYCKPLKEFVEA 253

  Fly   263 ALTKNPKKRPTAERLLQHPFVQCEMSLRVAK------ELLQKYQ 300
            .|.|.|..||||:.||:|..:     :|.||      ||:.||:
Zfish   254 CLNKEPSFRPTAKELLKHKLI-----VRFAKKTSYLTELIDKYK 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	128/258 (50%)
		S_TKc	26..283	CDD:214567	128/257 (50%)
		CNH	869..1184	CDD:279162
stk24b	XP_005165890.1	STKc_MST3_like	22..295	CDD:270786	135/284 (48%)
stk24b	XP_005165890.1	S_TKc	24..274	CDD:214567	128/257 (50%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910