DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and mbt

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_523375.2	Gene:	mbt / 32631	FlyBaseID:	FBgn0025743	Length:	639	Species:	Drosophila melanogaster

Alignment Length:	269	Identity:	109/269 - (40%)
Similarity:	161/269 - (59%)	Gaps:	8/269 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 ISRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRDCRHP 81
            :|..:|::..:...|||.|:.|.|..|....:....|:|.:.|......:::..|:::|||..||
  Fly   359 VSAGDPRENLDHFNKIGEGSTGTVCIATDKSTGRQVAVKKMDLRKQQRRELLFNEVVIMRDYHHP 423

  Fly    82 NIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVT-GPLTEVQIAYMCRETLKGLEYLHSMGKMHR 145
            ||:..|.|:|..|:||:.||:..||:|.||  || ..:.|.|||.:|::.||.|.||||.|.:||
  Fly   424 NIVETYSSFLVNDELWVVMEYLEGGALTDI--VTHSRMDEEQIATVCKQCLKALAYLHSQGVIHR 486

  Fly   146 DIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWAC 210
            |||..:|||...|.|||:|||..||::..:.||||.:||||||:|||.:   :..|....|||:.
  Fly   487 DIKSDSILLAADGRVKLSDFGFCAQVSQELPKRKSLVGTPYWMSPEVIS---RLPYGPEVDIWSL 548

  Fly   211 GITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAE 275
            ||..||:.:.:||.|:..|::|:..:  ...:||.|.|..|.||...:|:...|.::|.:|.||.
  Fly   549 GIMVIEMVDGEPPFFNEPPLQAMRRI--RDMQPPNLKNAHKVSPRLQSFLDRMLVRDPAQRATAA 611

  Fly   276 RLLQHPFVQ 284
            .||.|||::
  Fly   612 ELLAHPFLR 620

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	106/258 (41%)
		S_TKc	26..283	CDD:214567	106/257 (41%)
		CNH	869..1184	CDD:279162
mbt	NP_523375.2	CRIB_PAK_like	9..54	CDD:238526
		STKc_PAK_II	360..620	CDD:270815	109/266 (41%)
		S_TKc	372..619	CDD:214567	106/253 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45438534
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840