Protein Alignment hppy and tnika

DIOPT Version :9

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_005163444.1
• Gene: tnika / 325042
• ZFINID: ZDB-GENE-030131-3767
• Length: 1419
• Species: Danio rerio
• Alignment Length: 1524
• Identity: 344/1524 - (22%)
• Similarity: 541/1524 - (35%)
• Gaps: 535/1524 - (35%)

  Fly    16 DISR-RNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRD-C 78
            |:|. |:|...:||::.:|:||||.|||.:.:::.:|||||.:.:...:: :.|:.||.|::. .
Zfish    14 DLSTLRDPAGIFELVELVGNGTYGQVYKGRHVKTGQLAAIKCMDVTGEEE-EEIKAEINMLKKYS 77

  Fly    79 RHPNIIAYYGSYLRR------DKLWICMEFCGGGSLQDIYQVT--GPLTEVQIAYMCRETLKGLE 135
            .|.||..|||:::::      |:||:.|||||.||:.|:.:.|  ..|.|...||:.||.|:||.
Zfish    78 HHRNIATYYGAFIKKNPPGVDDQLWLVMEFCGAGSVTDLIKNTKGNSLKEDWTAYISREILRGLT 142

  Fly   136 YLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERK-- 198
            :||....:||||||.|:||||..:|||.|||||||:..|:::|.:||||||||||||.|.:..
Zfish   143 HLHQHKVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVSRRNTFIGTPYWMAPEVIACDENPD 207

  Fly   199 GGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTA 263
            ..|:...|:|:.||||:|:||..||:.:|||||||||:.::.  ||.|.:| ||:..||:||::.
Zfish   208 ATYDYKSDLWSLGITALEMAEGAPPLCELHPMRALFLIPRNA--PPRLKSK-KWTKRFHSFIESC 269

  Fly   264 LTKNPKKRPTAERLLQHPFVQ---CEMSLRVAK----ELLQKYQSPNPQFYYYLDGDEE------ 315
            |.||...||..::||:|||::   .|.::|:..    :..:|.:....:..|...|.||
Zfish   270 LVKNHNMRPGTDQLLKHPFIRDMANERTIRIQLKDHIDRTRKKRGERDETEYEYSGSEEEEEAML 334

  Fly   316 ------SVAGVP-----------QRIASK-----------------------MTSRTNGVPAQN- 339
                  |:..:|           .::|:|                       :..|...:..|.
Zfish   335 EIGEPSSIINIPGESTLRRDFLRLQVANKERSDALRRQQLEQQQNEGHKHQLLAERQKRIEEQKE 399

  Fly   340 -------------------------HTLKTGMTTNSTWNERSSSPETLPSDMSLLQYIDEELKLR 379
                                     ..|:..........|:......|..:...|:.:.::|...
Zfish   400 QRRRLEEQQRREREARKQQEQRHRYEELRREEERRQAEREQEYIRRQLEEEQRQLEILQQQLLQE 464

  Fly   380 ATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGTTHHQHQQ 444
            ..|.|....|                                                   |.::
Zfish   465 QALLLEYKRK---------------------------------------------------QVEE 478

  Fly   445 HHQHHHHPNHLHQHQSH--QLPQQQQQQSHQAAQQE----HHH----------------HHP--- 484
            ..|.......|.|.:::  .|.||||||...:..:|    :|:                |.|
Zfish   479 QRQADRLQRQLQQERAYLVSLQQQQQQQQQDSRPEEKKQLYHYKDAVNPSDKPAWAKKIHGPPQI 543

  Fly   485 --------------------------------MTSSISSGLVTANANNI------------SSSA 505
                                            :..|:...|.....|.|            :...
Zfish   544 KIQPSNRKQSTPLYYKLDNLGIPIGRAILNPSINQSVMQPLKPQKQNLIQRQSISPPPQYSAKKI 608

  Fly   506 SLASMPGLS----------AYLGMRS-----HVVGH---------MGMGFGMGLGMSNLRT---- 542
            |:...||.|          :.|..:|     |.|.:         ....|..| ||...||
Zfish   609 SMGPRPGFSRPPYKRVEERSKLNRQSSPALQHKVANRISDPSLPPRSESFSSG-GMQPARTPPMH 672

  Fly   543 -------------------------------TSIDADDDELVA--ADVAMNNA------------ 562
                                           ..:.|..:.||:  .::...|:
Zfish   673 RPVEPQMAHLVPVRSHSSSMSVSQSLHDQSAKGVSAFQESLVSNRPEMPRQNSDPTSEMPPPAPR 737

  Fly   563 ----------------AAAVPGNGSGA--------------------GNGSGSGCSASAAHYL-- 589
                            ..|||...||.                    |||..||...||:..:
Zfish   738 MASHEEKPDRSSPWLREDAVPPKLSGTTQVPQRTTSISPALARKNSPGNGESSGGGRSASQLIRT 802

  Fly   590 -----------------RYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHA------------P 625
                             |.|||..|:::..:||......:|..|...|.|.:            |
Zfish   803 SNPDLRRTELSLDVALQRTSSNSSSSSSTPSSQGGSQPGSSERNQPRGSGKSEGSPVALQETSKP 867

  Fly   626 I------TSSISSSASSASFYNRL--LLLDNSSGDAVVGGNGGGSSNISSSGGASSGTNGLLDKH 682
            |      .|..|..|...:....|  |.:|..|...:...:...||..|.|.....||.|.....
Zfish   868 IQEEGRELSKPSRPADLTALAKELRELRIDEVSRPPLKLTDYSSSSEDSDSSEDEDGTVGHDGTV 932

  Fly   683 ELDALPQAATKSAGDG----FSHSNSPTAN----SGAGATGSRDND-------GPSSSNSSH-LY 731
            .:..:|:......|:.    .||.:|.|.:    |..|....|:|:       |.|:..:.| ..
Zfish   933 SVSDIPRIMPSVQGNNESFTSSHDDSLTDSYNDESKDGTLRMRENNERQRLGHGESNGFAGHGNL 997

  Fly   732 QNLLRSSSGETPAGSSSAGNNCDYRHENNQNGLEDSPRRHSSMDQLIGLLENMGKS------PRT 790
            .:||:.|  .:|:|:.:..|:.|.                .|||: .||......|      ||.
Zfish   998 PDLLQQS--HSPSGTPTGLNSQDL----------------DSMDE-FGLGGGSKASFTPFVDPRV 1043

  Fly   791 RSLSDGGTQDDDEAEKEAQ--PDLLNNTPPVPPKRSHKRRHTPPRPIS------NGLPP---TPK 844
            ...|.  |.|:||:...|.  .:||         |..:.:....|.||      ..:.|   ||:
Zfish  1044 YQTSP--TDDNDESSAAAMFANELL---------RQEQAKLNEARKISVVNVNPTNIRPHSDTPE 1097

  Fly   845 VHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEG-----------IYNLNMNELHDAA 898
            :..   :.|.||.   .:.|.|.|      ..:||:|.|.|           :|||
Zfish  1098 IRK---YKKRFNS---EILCAALW------GVNLLVGTENGLMLLDRSGQGKVYNL--------- 1141

  Fly   899 IDQLFPRRTTWLYVIK--DVLMSLSGKSCQLYRHDLVALHSKQTVRFSLHMNKIPERLVPRKFAL 961
               :..||...:.|::  :||:::|||..:|..:.|..|.::     .||.:  ||  |.:|...
Zfish  1142 ---ITRRRFQQMDVLEGLNVLVTISGKKNKLRVYYLSWLRNR-----ILHND--PE--VEKKQGW 1194

  Fly   962 TTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWY-DPLNKFMLLKQCEWPAISIQGGGH 1025
            .| |.:.:.|....|.:  |...|:|..|..:.:.:..|. .|.:|||..|.
Zfish  1195 IT-VGELEGCIHYKVVK--YERIKFLVIALKNSVEIYAWAPKPYHKFMAFKS------------- 1243

  Fly  1026 GCVQNGHTPVFEMIITPELEYPIVCTGVR-KAMNG-CLKLELINMNSASWF------HSEDLEYD 1082
                     ..|:...|:|....|..|.| |.:.| .:...:|:::|.|.:      |.:.....
Zfish  1244 ---------FTELQHRPQLVDLTVEEGQRLKVIYGSSVGFHVIDVDSGSPYDIYIPSHIQSTVTP 1299

  Fly  1083 AMATMVPRRDLLKVVRVHQVEKDAILV-CYGNLIQVVTLQGNPKQHKKMVSQLNFDFNVDSIVCL 1146
            ....::|:.|.::::..:  |.:.:.| .||.:.:.|.||...                     :
Zfish  1300 HAIVVLPKTDGMEMLLCY--EDEGVYVNTYGRITKDVVLQWGE---------------------M 1341

  Fly  1147 PDSVLAFHKHGMQGKSLRNGEVTQEIKDM 1175
            |.||...|.:.:.|.    ||...||:.:
Zfish  1342 PTSVAYIHSNQIMGW----GEKAIEIRSV 1366

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	124/268 (46%)
		S_TKc	26..283	CDD:214567	124/267 (46%)
		CNH	869..1184	CDD:279162	69/330 (21%)
tnika	XP_005163444.1	PKc_like	18..313	CDD:304357	130/298 (44%)
		S_TKc	25..289	CDD:214567	124/267 (46%)
		CNH	1101..1399	CDD:214481	75/348 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910