DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and Stk26

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	XP_017457580.1	Gene:	Stk26 / 317589	RGDID:	1563568	Length:	630	Species:	Rattus norvegicus

Alignment Length:	414	Identity:	159/414 - (38%)
Similarity:	232/414 - (56%)	Gaps:	45/414 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MAAAHSHHNANMLSSDISRRN---PQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPS 62
            :|||...|:...:.....:.|   |::.:..:::||.|::|:|:|....::.::.|||:|.||.:
  Rat   210 VAAASMAHSPVAVQVPGMQNNIADPEELFTKLERIGKGSFGEVFKGIDNRTQQVVAIKIIDLEEA 274

  Fly    63 -DDIQIIQQEIIMMRDCRHPNIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYM 126
             |:|:.|||||.::..|....:..||||||:..||||.||:.||||..|:.: .||..|.|||.|
  Rat   275 EDEIEDIQQEITVLSQCDSSYVTKYYGSYLKGSKLWIIMEYLGGGSALDLLR-AGPFDEFQIATM 338

  Fly   127 CRETLKGLEYLHSMGKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPE 191
            .:|.||||:||||..|:|||||.||:||:|.||||||||||:.|:|.|..||.:|:|||:|||||
  Rat   339 LKEILKGLDYLHSEKKIHRDIKAANVLLSEQGDVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPE 403

  Fly   192 VAAVERKGGYNQLCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTF 256
            |.   ::..|:...|||:.||||||||:.:||..|:||||.|||:.|:  .||||  ...::.:|
  Rat   404 VI---QQSAYDSKADIWSLGITAIELAKGEPPNSDMHPMRVLFLIPKN--NPPTL--VGDFTKSF 461

  Fly   257 HNFIKTALTKNPKKRPTAERLLQHPF-VQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGV 320
            ..||...|.|:|..||||:.||:|.| |:.........||:.:::....:.:    .||||.:
  Rat   462 KEFIDACLNKDPSFRPTAKELLKHKFIVKNSKKTSYLTELIDRFKRWKAEGH----SDEESDS-- 520

  Fly   321 PQRIASKMTSRTNGVPAQNHTLKTGMTTNSTWN----ERSSSPETLPSDMSLLQYIDEELKLRAT 381
             :...|:.:||.:             .|:..|:    .:...|:.|.:        .||..|..|
  Rat   521 -EGSDSESSSRES-------------NTHPEWSFTTVRKKPDPKKLQN--------GEEQDLVQT 563

  Fly   382 LPLNNDTKDPLGAECSCSSHNGGA 405
            |...:....|..||......|..:
  Rat   564 LSCLSMIITPAFAELKQQDENNAS 587

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	130/259 (50%)
		S_TKc	26..283	CDD:214567	130/258 (50%)
		CNH	869..1184	CDD:279162
Stk26	XP_017457580.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910