DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and sid1

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_593564.1	Gene:	sid1 / 2542746	PomBaseID:	SPAC9G1.09	Length:	471	Species:	Schizosaccharomyces pombe

Alignment Length:	364	Identity:	142/364 - (39%)
Similarity:	210/364 - (57%)	Gaps:	33/364 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 DEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPS-DDIQIIQQEIIMMRDCRHPNIIAYY 87
            :.|.|::|:|||::|.|:||:...|.::.|||.|.||.. |||..|:||:.|:.:|...|:|.||
pombe     7 NSYTLLRKLGSGSFGVVWKARENVSGDIIAIKQIDLETGIDDITDIEQEVFMLSNCNSSNVIQYY 71

  Fly    88 GSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRDIKGANI 152
            |.::....|||.||...|||:..:.:: |.|.|..|:.:.||.|.||.|||...|:|||||.|||
pombe    72 GCFVDGYTLWILMEHMDGGSVSGLLKM-GRLNEQVISIILREVLYGLNYLHGQNKIHRDIKAANI 135

  Fly   153 LL-TEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACGITAIE 216
            || :..|:||||||||:||::...::|.:|:|||:||||||.   ::..|....|||:.||||||
pombe   136 LLSSSTGNVKLADFGVAAQLSNAASRRHTFVGTPFWMAPEVI---QQTSYGLAADIWSLGITAIE 197

  Fly   217 LAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAERLLQHP 281
            :|...||...:||||.:|.:.:|  :||.|:  |.:||||.:|:...|..||..|.:|:.|||||
pombe   198 MANGIPPRATMHPMRVIFEIPQS--EPPKLD--DHFSPTFRDFVSCCLDLNPNMRWSAKELLQHP 258

  Fly   282 FVQCEMSLRVAKELLQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTS-----RTNGVPAQNHT 341
            |::...:::....||  .|..|..|    |..::||  :.:.|.:.:..     .......::.|
pombe   259 FIKSAGTVKDIIPLL--VQKENKLF----DDSDQSV--LEETINNTLKPFEEPIAEGNADIEDWT 315

  Fly   342 LKTGMTTNSTWNERSSSP----------ETLPSDMSLLQ 370
            .:|...::||....:|.|          |.|||.:..|:
pombe   316 FETVKKSDSTVLGNTSIPKNSIISSQNKEELPSSIKYLE 354

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	121/259 (47%)
		S_TKc	26..283	CDD:214567	121/258 (47%)
		CNH	869..1184	CDD:279162
sid1	NP_593564.1	STKc_MST3_like	7..279	CDD:270786	125/281 (44%)
sid1	NP_593564.1	S_TKc	9..260	CDD:214567	121/258 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48012
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.010