DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment hppy and stk26

DIOPT Version :9

Sequence 1:	NP_725863.1	Gene:	hppy / 37203	FlyBaseID:	FBgn0263395	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_001120949.1	Gene:	stk26 / 100151762	ZFINID:	ZDB-GENE-080516-5	Length:	412	Species:	Danio rerio

Alignment Length:	326	Identity:	143/326 - (43%)
Similarity:	208/326 - (63%)	Gaps:	34/326 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 SRRNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPS-DDIQIIQQEIIMMRDCRHP 81
            ||.:|::.:..:.:||.|::|:|:|....|:..:.|||.|.||.: |:|:.|||||.::..|..|
Zfish    16 SRTDPEELFTKLDRIGKGSFGEVFKGIDRQTQNVVAIKTIDLEEAEDEIEDIQQEITVLSQCDSP 80

  Fly    82 NIIAYYGSYLRRDKLWICMEFCGGGSLQDIYQVTGPLTEVQIAYMCRETLKGLEYLHSMGKMHRD 146
            ::..||||||:..||||.||:.||||..|:.: .||..|.|||.|.:|.||||:||||..|:|||
Zfish    81 HVTKYYGSYLKGSKLWIIMEYLGGGSALDLLR-AGPFDEYQIATMLKEILKGLDYLHSEKKIHRD 144

  Fly   147 IKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERKGGYNQLCDIWACG 211
            ||.||:||:|.|:||||||||:.|:|.|..||::|:|||:||||||.   ::..|:...|||:.|
Zfish   145 IKAANVLLSESGEVKLADFGVAGQLTDTQIKRETFVGTPFWMAPEVI---QQSAYDSKADIWSLG 206

  Fly   212 ITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNPKKRPTAER 276
            |||||||:.:||..|:||||.||.:.|:  .|||||.  .:|..|..|:.:.|.|:|..||||:.
Zfish   207 ITAIELAKGEPPNSDMHPMRVLFHIPKN--TPPTLNG--DFSKIFKEFVDSCLNKDPAFRPTAKE 267

  Fly   277 LLQHPFVQCEMSLRVAK---------ELLQKYQSPNPQFYYYLDGDEESVAGVPQRIASKMTSRT 332
            ||:|.|:     ::.||         :.|:::::..     :.||:..|.:.      |:.:|:.
Zfish   268 LLKHKFI-----VKYAKKTSYLTELIDRLKRWKAEG-----HSDGESSSDSD------SETSSKD 316

  Fly   333 N 333
            |
Zfish   317 N 317

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	130/258 (50%)
		S_TKc	26..283	CDD:214567	130/257 (51%)
		CNH	869..1184	CDD:279162
stk26	NP_001120949.1	STKc_MST3_like	22..295	CDD:270786	134/285 (47%)
stk26	NP_001120949.1	S_TKc	24..274	CDD:214567	130/257 (51%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910