Protein Alignment hppy and mink1

DIOPT Version :9

• Sequence 1: NP_725863.1
• Gene: hppy / 37203
• FlyBaseID: FBgn0263395
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_021331645.1
• Gene: mink1 / 100038799
• ZFINID: ZDB-GENE-060526-45
• Length: 1314
• Species: Danio rerio
• Alignment Length: 1360
• Identity: 325/1360 - (23%)
• Similarity: 515/1360 - (37%)
• Gaps: 404/1360 - (29%)

  Fly    20 RNPQDEYELIQKIGSGTYGDVYKAKRIQSNELAAIKVIKLEPSDDIQIIQQEIIMMRD-CRHPNI 83
            |:|...:||::.:|:||||.|||.:.:::.:||||||:.:...:: :.|:.||.|::. ..|.||
Zfish    19 RDPAGIFELVEVVGNGTYGQVYKGRHVKTGQLAAIKVMDVTEEEE-EEIKAEINMLKKYSHHRNI 82

  Fly    84 IAYYGSYLRR------DKLWICMEFCGGGSLQDIYQVT--GPLTEVQIAYMCRETLKGLEYLHSM 140
            ..|||:::::      |:||:.|||||.||:.|:.:.|  ..|.|..|||:|||.|:||.:||:.
Zfish    83 ATYYGAFVKKSPPGHDDQLWLVMEFCGAGSVTDLVKNTKGNSLKEDWIAYICREILRGLSHLHAH 147

  Fly   141 GKMHRDIKGANILLTEYGDVKLADFGVSAQITATINKRKSFIGTPYWMAPEVAAVERK--GGYNQ 203
            ..:||||||.|:||||..:|||.|||||||:..|:.:|.:||||||||||||.|.:..  ..|:.
Zfish   148 KVIHRDIKGQNVLLTENAEVKLVDFGVSAQLDRTVGRRNTFIGTPYWMAPEVIACDENPDSTYDY 212

  Fly   204 LCDIWACGITAIELAELQPPMFDLHPMRALFLMSKSGFKPPTLNNKDKWSPTFHNFIKTALTKNP 268
            ..|||:.||||||:||..||:.|:||||||||:.::  .||.|.:| |||..|.:||:..|.|:.
Zfish   213 RSDIWSLGITAIEMAEGAPPLCDMHPMRALFLIPRN--PPPKLKSK-KWSKKFIDFIEGCLVKSY 274

  Fly   269 KKRPTAERLLQHPFV-------QCEMSL-----RVAKELLQKYQSPNPQFYYYLDGDEE------ 315
            ..||:.|:||:|.|:       |..:.|     |..|:..:|.::.    |.|...|||
Zfish   275 PNRPSTEQLLKHSFIRDQPTERQVRIQLKDHIDRTRKKRGEKEETE----YEYSGSDEEDENRGD 335

  Fly   316 -----SVAGVP---------QRIASKMTSRTNGVPAQNHTL------------------------ 342
                 |:..||         .|:..:...|:..:..|...|
Zfish   336 ERESSSILNVPGESTLRRDFLRLQQENKERSEALKRQQAQLAAQRRDPEEHKRQLLHDRQKRIEE 400

  Fly   343 ----------KTGMTTNSTWNERSSSPETLPSDMS--------------LLQYIDEE-------- 375
                      :..........::..:|.....||.              :...::||
Zfish   401 QKEQRRRLEEQQRKEREMVRQQQDKAPHRRLDDMRREEDRRLAEREQEFIRHKLEEEQRQLEILQ 465

  Fly   376 ---LKLRATLPLNNDTKDPLGAECSCSSHNGGAAGGGGGGGVGVGAGGAAANGSSSSSGGATVGT 437
               |:.:|.|.|.|       ..||.||.|                                 ..
Zfish   466 QQLLQEQALLMLYN-------KHCSDSSVN---------------------------------EY 490

  Fly   438 THHQHQQHHQHHHHPNHLHQHQSHQLPQQQQQQSHQAAQQEHHHHHPMTSSISSG---------- 492
            ...|.::..|.......|.|..::.:..|||||......|.:|:...:.::..:.
Zfish   491 KRKQLEEQRQSERLQRQLQQEHAYLVSLQQQQQQQDKKPQMYHYSKNLENNKPAWAREVEERSKL 555

  Fly   493 --------LVTANANNISSSASLASMPGLSAYLGMRSHVVGHMGMG-FGM--------------- 533
                    ..|.:..||.|.:...:..|.:....|:..|....|.| |.|
Zfish   556 NRQGSPKICTTVSDTNIQSRSESINQSGAAQTPPMQRPVEPQGGQGKFQMAHLVPLKPYAAPVPR 620

  Fly   534 --GLGMSNLRTTSIDADDD-------------ELVAADVAMNNAAAA------------------ 565
              .|.....:|.|.....|             |||..:....:...|
Zfish   621 SQSLCDQPTKTMSAFPTQDPSPTPTPRPLHSRELVRQNSDPTSETPAPQSRPMRDDRGPWIRLPE 685

  Fly   566 ------VPGNGSGAGNGSGSGCSASAAHYLRYSSNYRSAAAAQASQAAHPHVNSNSNSNNGHGHA 624
                  :|...:.......:..|:...|.:|               |::|.::.|.....|.
Zfish   686 IEQPPKIPQRTASIATALNTNLSSGIRHPVR---------------ASNPDLSRNERWERGD--- 732

  Fly   625 PITSSISSSASSASFYNRLLLLDNSSGDAVV-----GGNGGGSSNISSSGG-------ASSGTNG 677
              :.||.|:........|..:|.:|..|:..     |.:..|.|..||...       |....:|
Zfish   733 --SMSIMSNLPQTGSLERHRILSSSKMDSSPTLSHDGRHKPGESRTSSRPSRPASYKRAIGEDHG 795

  Fly   678 LLDKHELDALPQAATKS---AGDGFSHSNSPTANSGAGATGSRDNDGPSSSNSSHLYQNLLRSSS 739
            |..|...:..|:...|:   :....|..:|..:.||.||......|.|..::|..:...::....
Zfish   796 LYSKERAEEQPRPPVKANDYSSSSESSESSEESESGEGAEEESPTDRPRDADSDSVNTMVVHEEE 860

  Fly   740 GETPAGSSSAGNNCDY----------RHENNQNGLED---------------SPRRHSSMD-QLI 778
            .........||...|.          |..|....|.|               ||.:.|:.| |..
Zfish   861 EGEGGEEERAGGYGDQTMLVQRTPEKRSHNGYTNLPDVVQPSHSPTDSASHSSPGKDSTYDYQSR 925

  Fly   779 GLLENMGKSPRTRSLS------DGGTQDD----------DEAEKEAQPDLLNNTPPVPPKRSHKR 827
            ||::..|||..|..:.      .||:.|:          ::.:.|.:...:.|..|
Zfish   926 GLVKASGKSSFTTFVDLGMYQPSGGSGDNISVGGLGSRFEQLKLEVRKGSMVNVNP--------- 981

  Fly   828 RHTPPRPISNGLPPTPKVHMGACFSKIFNGCPLRVHCTASWIHPETRDQHLLIGAEEGIYNLNMN 892
              |..||:|:    ||::..   :.|.||.   .:.|.|.|      ..:||:|.|.|:..|:.
Zfish   982 --TNTRPVSD----TPEIRK---YKKRFNS---EILCAALW------GVNLLVGTENGLKLLDR- 1027

  Fly   893 ELHDAAIDQLFP----RRTTWLYVIK--DVLMSLSGKSCQLYRHDLVALHSKQTVRFSLHMNKIP 951
                :...:::|    ||...:.|::  ::|:::|||..::..:.|..|.:|     .||.:  |
Zfish  1028 ----SGQGKVYPLINSRRFQQMDVLEGLNLLITISGKKNKVRVYYLAWLRNK-----ILHND--P 1081

  Fly   952 ERLVPRKFALTTKVPDTKCCTQCCVTRNPYNGYKYLCGATPSGIFLMQWY-DPLNKFMLLKQC-E 1014
            |  |.:|...|| |.:.:.|....|.:  |...|:|..|..:.:.:..|. .|.:|||..|.. :
Zfish  1082 E--VEKKQGWTT-VGEMEGCVHYKVVK--YERIKFLVIALKNAVEVYAWAPKPYHKFMAFKSFGD 1141

  Fly  1015 WPAISIQGGGHGCVQNGHTPVFEMIITPELEYPIVCTGVRKAMNGCLKLELINMNSASWFHSEDL 1079
            .|               |.||...:...|.:                :|::| ..|.:.||:.|:
Zfish  1142 LP---------------HRPVLVDLTVEEGQ----------------RLKVI-YGSLAGFHAIDV 1174

  Fly  1080 E----YDA-------------MATMVPRRDLLKVVRVHQVEKDAILV-CYGNLIQVVTLQ 1121
            :    ||.             ....:|..|.::::..:  |.:.:.| .||.:|:.|.||
Zfish  1175 DSGNNYDIYIPVHIQSQITPHAIVFLPNSDGMEMLLCY--EDEGVYVNTYGRIIKDVVLQ 1232

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hppy	NP_725863.1	STKc_MAP4K3_like	25..283	CDD:270788	128/268 (48%)
		S_TKc	26..283	CDD:214567	128/267 (48%)
		CNH	869..1184	CDD:279162	61/279 (22%)
mink1	XP_021331645.1	STKc_MAP4K4_6_N	8..289	CDD:270806	130/273 (48%)
		CNH	996..1294	CDD:214481	67/297 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.910