Protein Alignment CG10737 and C2cd2l

DIOPT Version :10

• Sequence 1: NP_001137711.1
• Gene: CG10737 / 37202
• FlyBaseID: FBgn0034420
• Length: 955
• Species: Drosophila melanogaster
• Sequence 2: NP_001346188.1
• Gene: C2cd2l / 71764
• MGIID: 1919014
• Length: 707
• Species: Mus musculus
• Alignment Length: 809
• Identity: 146/809 - (18%)
• Similarity: 261/809 - (32%)
• Gaps: 223/809 - (27%)

  Fly   100 GLDLSKPLAGASGGRGRSSASPLNTAGAAAG-GPRRRVVRQSSTGPENRKKRYVPPPSNVVGPET 163
            ||.||:    |.|||....||.....|:... |..|.::|..:|      :...|..:.|.|...
Mouse    36 GLWLSR----ADGGRDSRPASAAEPGGSLRELGVWRSLLRLRAT------RTSTPEEAGVRGLLA 90

  Fly   164 SSVTWTSQVFRWLYSDLVIVNELLMSWVIAINDTLRKSVEEHGVAVEVVRVLPDSPAPGLNNIFC 228
            |...:.|....|           ..:||.|:|:...:......:|.|.:..||  |...::::
Mouse    91 SLFAFKSFRENW-----------QRAWVRALNEQACRDGSSIQIAFEEIPQLP--PRASISHV-- 140

  Fly   229 NCDENNPADMLITFDCDAMPV-LQVKTFRQKSGKVETSHYKVTVSRFRARMAIPMNYNSLKGEMR 292
            .|.:.:...|::.....|..| ..:...:|....|....|.||::....::           |:.
Mouse   141 TCVDQSERTMVLHCQLSAEEVRFPISVTQQSPAAVSMETYHVTLTLPPTQL-----------EVS 194

  Fly   293 VEGYPD------------VRIAMNSVGAIKAMDQDEQQLQ-TVISDILTTALRDTIYPVDFSIYS 344
            :|..||            ..:::..:..::..::||:|.: :.:.:::..|:..|...:..::.:
Mouse   195 LEEIPDEGLLVSWAFTDRPELSLKVLPKLQTRERDEEQPELSTVEELIKDAIVSTQPAMMVNLRA 259

  Fly   345 TCPRAEVEPLDLPVIYPVHYDSLAHNMEQHMGGVGLRDSQHMVSGRRLLVKIVK----GDGIRDA 405
            ......:.|.:.|           ..|.|....:        ....||.::.::    |..:...
Mouse   260 CSAPGGLVPSEKP-----------PTMSQAQPSI--------PRPTRLFLRQLRASHLGSELGGT 305

  Fly   406 QNPYVVIEMDEPAQKNQTGTQRGGKPF-WDEHFLFELSPQSAEILFEVYDHPVIASDPPKFLGLG 469
            :......|:|.|.|:..|...|.|... |.|....:|.|||.|:..:|.          :....|
Mouse   306 EELCCAAELDNPMQQKWTKPMRAGPEVEWTEDLALDLGPQSRELTLKVL----------RSSSCG 360

  Fly   470 ---LVGIDELAVGPAS-----TQLLQLQPRPYETQPVSGAITVDFVFIEGAEIPAGARPQRLKEA 526
               |:|...|.||..|     .|:..|.|.|.::...:..:|.:..:.:|:       |:.|
Mouse   361 DAELLGQATLPVGSPSRPMSRRQVCPLTPGPGKSLSPAATVTAELHYEQGS-------PRNL--- 415

  Fly   527 LRLSTPAINEHIRNGADLADAAVRALQDGALSSSGSGGQPSKSTLIIHSVQRNSSSPNAFKVELN 591
                                                 |.|:.||      .|.|.:|.. |:||:
Mouse   416 -------------------------------------GTPTSST------PRPSITPTK-KIELD 436

  Fly   592 R----DGQIEVTDTATELDQAVAQAFERAANEAQTELELELAKEEKSSQLGEPLIDSGNGTVNEE 652
            |    ||.:..|.|..:                        ::.....:|..|........|.|:
Mouse   437 RTIMPDGTVVTTVTTVQ------------------------SRPRVDGKLDSPSRSPSKVEVTEK 477

  Fly   653 STAEFGQPNAASSPNGSSYHNNYSLNGNGNSNGAGSGGYNSLPRNGGAQQLAQQSGLLEGHDVVD 717
            .|....:.:..|:.:.||......|     |||.......::      :||.:.||
Mouse   478 MTTVLSESSGPSNASHSSSPGESHL-----SNGLDPVAETAI------RQLTEPSG--------- 522

  Fly   718 DRGRSKKRNFFGTLKKRLSRSKTRTLSADQPNNNSHKSLSATNSNTTTATGFPRTATGTLNGDSS 782
                       ...||..::..|..:|.......:...|:.:.....:.....:...||..|.||
Mouse   523 -----------RAAKKTPTKRSTLIISGVSKVPIAQDELALSLGYAASLEASMQDDAGTSGGPSS 576

  Fly   783 RSLSVDRATLSKSNSLGPRMGIGHSITDHSRRSSISESSAISGFSSASNKTYVHEASTLVLETIE 847
            ........:....::|.....:..:  |.:.||.|||..::....|.:       .||..|||
Mouse   577 PPSDPSATSPGPVDALSSPTSVQEA--DETTRSDISERPSVDDVESET-------GSTGALET-- 630

  Fly   848 NGIKRHFI------VPLAIAQRPRWRRKG 870
            ..:|.|.:      ..|...:|||.:..|
Mouse   631 RSLKDHKVSFLRSGTKLIFRRRPRQKEAG 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10737	NP_001137711.1	SMP_SF	168..335	CDD:459248	28/180 (16%)
		C2_C21orf25-like	392..515	CDD:176060	30/135 (22%)
		C1_dGM13116p-like	874..932	CDD:410381
C2cd2l	NP_001346188.1	SMP_C2CD2L	84..260	CDD:439239	32/201 (16%)
		C2	288..412	CDD:472691	30/140 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	408..430		9/74 (12%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	565..683		25/106 (24%)