Protein Alignment CG10737 and LOC4577642

DIOPT Version :10

• Sequence 1: NP_001137711.1
• Gene: CG10737 / 37202
• FlyBaseID: FBgn0034420
• Length: 955
• Species: Drosophila melanogaster
• Sequence 2: XP_061517006.1
• Gene: LOC4577642 / 4577642
• VectorBaseID: AGAMI1_010059
• Length: 980
• Species: Anopheles gambiae
• Alignment Length: 1085
• Identity: 406/1085 - (37%)
• Similarity: 557/1085 - (51%)
• Gaps: 253/1085 - (23%)

  Fly     2 DLADQIDDYICSFEGLGDLTMDSLAIFIFLWAVLALFSVWLIKLLYHKY-LNKDKSASAANSRQT 65
            |||||||||||.|||.||||||:..:.:|...|:.:..|:..||:|.|| |.|..:|:...:...
Mosquito     4 DLADQIDDYICVFEGAGDLTMDTFVMLLFALIVVVISLVFATKLIYDKYVLKKGATATGGTADGV 68

  Fly    66 SVAPT----SGSPTSVAGKTE-KRLSEPRDLLATKSKVEGLDLSKPLAGASGGRGRSSASPLNTA 125
            ..|.|    :.:|...||.|. .|:|||:::|:.|..:    ||:...|.|||.|..........
Mosquito    69 GTAATVPAGTATPLVSAGVTAGTRVSEPKEVLSKKEAI----LSQVRNGGSGGMGGGGGGARGGG 129

  Fly   126 G------AAAGGP---RRRVVRQSSTGPENRKKRYVPPPSNVVGPETSSVTWTSQVFRWLYSDLV 181
            |      .||.||   |:|:.|. |.|||.:|||.|.||||:.|.:.....|...:|||||||||
Mosquito   130 GFGGGAMGAASGPMIARKRISRM-SPGPEAQKKRPVIPPSNINGTDPQITQWAIHLFRWLYSDLV 193

  Fly   182 IVNELLMSWVIAINDTLRKSVEEHGVAVEVVRVLPDSPAPGLNNIFCN-CDENNPADMLITFDCD 245
            :||:||..||..:|..|...||:|.:.||||||||:|..|.:::|.|. .|:.|..::|  ||.|
Mosquito   194 VVNKLLQDWVATVNTALLTHVEQHEMIVEVVRVLPESLPPNMSSILCEPTDQPNEVELL--FDVD 256

  Fly   246 AMPVLQVKTFRQKSGKVETSHYKVTVSRFRARMAIPMNYNSLKGEMRVEGYPDVRIAMNSVGAIK 310
            |.||||:|.|:..:.|.|.||||.||:|.::|:::.:||.:|||||::|||||::|.:||:|.:|
Mosquito   257 ATPVLQIKAFKSSNQKTEVSHYKATVARLKSRVSVIVNYFALKGEMKLEGYPDIKIHLNSIGPLK 321

  Fly   311 -AMDQDEQQLQTVISDILTTALRDTIYPVDFSIYSTCPR---AEVEPLDLPVIYPVHYDSLAHNM 371
             |..|||::...:|:::|..::||.:|||||||||||||   .|.|.:.....|..:.|.. ...
Mosquito   322 TANAQDEKKQIDLITELLIGSMRDVVYPVDFSIYSTCPRIMGEESEEVTSDYGYGGYSDGY-RGY 385

  Fly   372 EQHMGGVGLRDSQHMVSGRRLLVKIVKGDGIRDAQNPYVVIEMDEPAQKNQTGTQRGGKPFWDEH 436
            :....|.||     ..|.|:||||:||.:|:.....|:.||||||||||:|:.::.|..|:|||.
Mosquito   386 QDDAYGTGL-----SASPRKLLVKVVKAEGLLKCSQPFCVIEMDEPAQKHQSASKLGQSPYWDET 445

  Fly   437 FLFELSPQSAEILFEVYDHPVIASD---------------------------------------- 461
            |||:||..|.|:||||||...:.:|
Mosquito   446 FLFDLSNHSTELLFEVYDTVAVGNDKTTSELREGTAGDDATSDDPQQVPSAAVNMASTASIPDVV 510

  Fly   462 --------------PP------------------------------------------------- 463
                          ||
Mosquito   511 DSTTNTRSETSAELPPVDNGSDGVLATVAECPEASDATENDPVEPLTTKTTPTPTVDSGGDEPAC 575

  Fly   464 ---------------KFLGLGLVGIDELAVGPASTQLLQLQPRPYETQPVSGAITVDFVFIEGAE 513
                           ||||||||||||||.|||:||:|:||||||||:.::|::||:||||:...
Mosquito   576 TDTNQSKPRNASGGQKFLGLGLVGIDELASGPATTQILELQPRPYETETITGSLTVEFVFIDSPP 640

  Fly   514 IPAGARPQRLKEALRLSTPAINEHIRNGADLADAAVRALQDGALSSSGSG--GQPSKSTLIIHSV 576
            :|| ||.|..:::.         |....::.|       :|...|:.|.|  |:.:.:..:::..
Mosquito   641 VPA-ARRQYNQQSF---------HANGMSNFA-------RDAVTSTPGPGSPGKTAANQAMVNGS 688

  Fly   577 QRNS-SSPNAFKVELNRDGQIEVTDTATELDQAVAQAFERAANEAQTELELELAKEEKSSQLGEP 640
            |.:| .||::...:|:...            ||:|:..:|........:.....|...:.||
Mosquito   689 QSSSPMSPSSPSKQLSNKA------------QAMAERNQRFQAAEANRMNNSFLKPTATGQL--- 738

  Fly   641 LIDSGNGTVNEESTAEFGQPNAASSPNGSSYHNNYSLNGNGNSNGAGSGGYNSLPRNGGAQQLAQ 705
              :|.||....|||.  ..| |.||.:.:|.....||     ||.| ....||.|
Mosquito   739 --NSLNGMGKSESTP--ASP-ALSSTSATSQSMTASL-----SNSA-PVSVNSAP---------- 782

  Fly   706 QSGLLEGHDVVDDRGRSKKRNFFGTLKKRLSRSKTRTLSADQPNNNSHKSLSATNSNTTTATGFP 770
                          ...|.||.||||:.:|:.||            ..|||.....:.||..|..
Mosquito   783 --------------PVKKPRNIFGTLRNKLTPSK------------KSKSLDVPQYSPTTPGGNV 821

  Fly   771 RTATGTLNGDSSRSLSVDRATLSKSNSLGPRMGIGHSITDHSRRSSISESSAISGFSSASNKTYV 835
            |:|:               :|||:.:|:..|..|..::   ||:|||||||||||.|:.|.:|||
Mosquito   822 RSAS---------------STLSRGSSIDQRSNIFRNL---SRKSSISESSAISGLSTGSGRTYV 868

  Fly   836 HEASTLVLETIENGIKRHFIVPLAIAQRPR-WRRKGTKLHIYNDHTFIAKHLSGSGLQCSICMKS 899
            ||.|||:|||.||.:.||::|||.:|.:.: |:||||||||||||||:|||:.| |:.|.:|.:|
Mosquito   869 HEESTLLLETTENNVVRHYLVPLEVATKQKNWKRKGTKLHIYNDHTFVAKHIPG-GILCFVCNRS 932

  Fly   900 IPRRPGKQGYECRDCQLISHKQCHIRAPQACPNPTVLSMELTSFP 944
            |||||||||||||||.:..||.||:|||||||||.:|||:|..:|
Mosquito   933 IPRRPGKQGYECRDCAIQCHKPCHVRAPQACPNPKILSMQLLRWP 977

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10737	NP_001137711.1	SMP_SF	168..335	CDD:459248	81/168 (48%)
		C2_C21orf25-like	392..515	CDD:176060	75/240 (31%)
		C1_dGM13116p-like	874..932	CDD:410381	41/57 (72%)
LOC4577642	XP_061517006.1	None