Protein Alignment CG10737 and C2cd2

DIOPT Version :10

• Sequence 1: NP_001137711.1
• Gene: CG10737 / 37202
• FlyBaseID: FBgn0034420
• Length: 955
• Species: Drosophila melanogaster
• Sequence 2: NP_777272.2
• Gene: C2cd2 / 207781
• MGIID: 1891883
• Length: 696
• Species: Mus musculus
• Alignment Length: 719
• Identity: 142/719 - (19%)
• Similarity: 236/719 - (32%)
• Gaps: 206/719 - (28%)

  Fly   153 PPPSNVVGPETSSVTWTSQVFRWLYSDLVIVNELLMSWVIAIN-------DTLRKSVEEH----- 205
            |||.....|:......:..:..|:.:.....|:...:||.|:|       ..||.|.::.
Mouse    38 PPPRRRAEPDELRRRESDTLLSWILTRDSWGNQWQAAWVTALNYEAEKRGGPLRLSFQKDPRPQS 102

  Fly   206 -GVAVEVVRVLPDSPAPGLNNIFCNCDENNPADMLITFDCDAMPVLQVKTFRQKSGKVETSHYKV 269
             .:.||.|..:..|....:  :.|:.     ....:.|...|.|.       ..:|. |...|.|
Mouse   103 LQLTVEKVSSVVKSTQEKV--VICHV-----VGETLQFLVSAGPA-------SATGS-ECQLYDV 152

  Fly   270 TVSRFRARMAIPMNYNSLKGEMRVEGYPDVRIAMNSV----GAIKAMDQDEQQLQTVISDILTTA 330
            .:|.|..::...|.          |...|::|..:..    .|||...|...:.|.:..::|:.|
Mouse   153 HLSPFHLKVEFHME----------EKREDIQIRWSFTHVPETAIKIQPQAPGEKQALGVNMLSEA 207

  Fly   331 LRD----TIYPVDFSIY-STCPR--AEVEPLDLPVIYPVHYDSLAHNMEQHMGGVGLRDSQHMVS 388
            |.|    .:.....|:: ||.|.  .|.:.|..|          :...::.......|..:..:.
Mouse   208 LEDLFKHLVNAASPSVFLSTKPTQVKEAQSLQCP----------SSTAQEPCPPKPPRAHELKLQ 262

  Fly   389 GRRLLVKIVKGDGIRDAQNPYVVIEMDEPAQ-------KNQTGTQRGGKPFWDEHFLFELSPQSA 446
            .:.:.|.::...|.....: ..|.::::|.|       :|.|...      |:|.|.|||:.:|.
Mouse   263 VKNIRVSLINHPGASGLSH-VCVAQLNDPEQRFISTLVRNTTDLS------WEEEFTFELNAKSK 320

  Fly   447 EILFEVYDHPVIASDPPKFLGLGLVGIDELAVGPASTQLLQLQPRPYETQPVSGAITVDFVFIEG 511
            |::.::...   .......||:..:.:|.....|...|..:|.........|.|::|.:|.::|.
Mouse   321 ELVLQISQD---GCSSEGLLGIATIHLDLFRKQPNGPQTFRLISGTEPDSLVLGSVTAEFSYVEP 382

  Fly   512 AEI---------------------PAG-------------------ARPQRLKEALR-------- 528
            .|:                     |.|                   |.|...:..:|
Mouse   383 GELKSWPAPPPVSAAKIEKDRTVMPCGTVVTTVTAVKTKPRFDTGRATPLNSESPVRTPVTVKVI 447

  Fly   529 ---LSTPAINEH----------------IRNGAD-LADAAVRALQDGALSSSGSGGQP-SKSTLI 572
               :|..||:.|                :.||:| :|:.|:|.|.:   ||......| .|||:|
Mouse   448 EKDISVQAISCHSAPVSKTFSSSDTELLVLNGSDPVAEVAIRQLSE---SSKLKLKSPRKKSTII 509

  Fly   573 IHSVQRNSSSP--NA-----FKVELNRDGQIEVTDTA--TELDQAVAQAFERAANEAQT------ 622
            |..:.:.|.|.  ||     :...::...|.:.|...  .|..:|.|.........|||
Mouse   510 ISGISKTSLSQDHNAALMLDYAASMDSTNQGDATSALCHPEATEASATTPPEENEPAQTLPALKP 574

  Fly   623 -ELEL---ELAKEEKSSQLGEPLIDSGNGTVNEESTAEFGQPNAASSPNGSSYHNNYSLNGNGNS 683
             |.:|   ||.||...:....|.:...:|....||:....:..|.....|
Mouse   575 RENDLDSWELEKESPVASWSGPALQEPDGDELSESSLSTSELGAMKKHKG--------------- 624

  Fly   684 NGAGSGGYNSLPRNGGA-------QQLAQQSGLLEGH-DVV---DDRGRSKKRNFFGTL--KKRL 735
                     .|.|.|..       ||  :..||.:.| |:|   ...||.||....|.|  :|.|
Mouse   625 ---------GLLRKGAKLFFRRRHQQ--KDPGLSQSHNDLVFLQQPEGRQKKGATLGRLLNRKLL 678

  Fly   736 SRSK 739
            :|.:
Mouse   679 TRHR 682

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10737	NP_001137711.1	SMP_SF	168..335	CDD:459248	36/187 (19%)
		C2_C21orf25-like	392..515	CDD:176060	27/150 (18%)
		C1_dGM13116p-like	874..932	CDD:410381
C2cd2	NP_777272.2	SMP_C2CD2	53..230	CDD:439238	39/201 (19%)
		C2	261..386	CDD:472691	27/134 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	551..611		15/59 (25%)