Protein Alignment CG10737 and tmem-24

DIOPT Version :10

• Sequence 1: NP_001137711.1
• Gene: CG10737 / 37202
• FlyBaseID: FBgn0034420
• Length: 955
• Species: Drosophila melanogaster
• Sequence 2: NP_741753.1
• Gene: tmem-24 / 180654
• WormBaseID: WBGene00020012
• Length: 901
• Species: Caenorhabditis elegans
• Alignment Length: 867
• Identity: 216/867 - (24%)
• Similarity: 354/867 - (40%)
• Gaps: 213/867 - (24%)

  Fly   160 GPETSSVTWTSQVFRWLYSDLVIVNELLMSWVIAINDTLRKSV---------EEHGVAVEVVRVL 215
            |..|||..|::::..||||:...|...:.:|:.::|:..:|..         |..|...:|::
 Worm   138 GTHTSSGEWSNEIVSWLYSNFHKVPAPMDAWIKSLNEAAKKVTSPTKCEVLFEGFGDHSDVLQ-- 200

  Fly   216 PDSPAPGLNNIFCNCDENNPADMLITFDCDAMPVLQVK--TFRQKSGKVETSHYKVTVSRFR--- 275
                .|.::|:..   |:.|.|.|.......:|.::::  :.::...::..|:|.|::...|
 Worm   201 ----PPKISNVRV---EHGPRDHLTVRSNVHLPCVKLRLVSSQRTPERMIVSNYDVSIVDLRGEV 258

  Fly   276 -ARMAIPMNYNSLKGEMRVEGYPDVRIAM-----NSVGAIKAMDQDEQQLQTVISDILTTALRDT 334
             .|||...|...|.|  ...|.|::.|.:     |:...:.....:|...:.::|.:....|.:.
 Worm   259 ECRMACIANQLYLMG--CFSGRPEMDIELRNTDPNAQYQVSIPMVEESIRRCLLSAVTNINLSEE 321

  Fly   335 IYPVDFSIYSTCPRAEVEPLDLPVIYPVH---------YDSLAHNMEQHMGGVGLRDS------- 383
            :.....:...|..|....|       |.|         |::...|:  |:...|.:.|
 Worm   322 MPEERNTFADTFSRTIYNP-------PTHSPSGTMRNSYNNYDTNL--HVDAYGTQSSHRSNSPS 377

  Fly   384 ------------QHMVS--------GRRLLVKIVKGDGI-RDAQNPYVVIEMDEPAQKNQTGTQR 427
                        .|::|        ..::.:|::|...: |:...|:|.:||||||||..|....
 Worm   378 GDVPEMFKKLNESHLISPSYNTNSIPNKMRIKVIKASRLGREVSQPFVNVEMDEPAQKYSTTKGI 442

  Fly   428 GGKPFWDEHFLFELSPQSAEILFEVYD--HPVIASDPPKFLGLGLVGIDELAVGPASTQLLQLQP 490
            ...|||:|.|.|:|:|.:.|||||:|:  ..:..:|...||||.:|..:|:.....:...|:||.
 Worm   443 NANPFWEETFDFDLTPATEEILFEIYEGNDKLHMNDDEGFLGLAIVNFEEIRRSGETVHSLKLQG 507

  Fly   491 RPYETQPVSGAITVDFVFIEGAEIPAGARPQRLKEALRLSTPAINEHIRNGADLADAAVRALQDG 555
            |||....:||.|||.|.|.....:....   :|.:.::::.|       ||::.
 Worm   508 RPYRKDAISGEITVQFDFFYDPNLLTSG---KLTDTVKVTNP-------NGSEF----------- 551

  Fly   556 ALSSSGSGGQPSKSTLIIHSVQRNSSSPNAFKVELNRDGQ--IEVTDTATELDQAVAQAFERAAN 618
                        :.||..|  :|....|:.     |.||.  |..:.|.|...:.|:|..:....
 Worm   552 ------------RETLTTH--RRPIYDPHD-----NFDGHEPIVPSKTTTVTVKTVSQTLKEKPT 597

  Fly   619 EAQTELELELAKEEKSSQLGEPLIDSGNGTVNEESTAEFGQPNAASSPNGSSYHNNYSLNGNGNS 683
            .......||.|.:..:.::.:....:.|.....|..|:.  .:.|.|.:.||..:..|.|||
 Worm   598 IQSVHGSLENAVDPATQKILDRQFKNHNDPKTRELEAKL--QSVAQSMSASSTLDRPSKNGN--- 657

  Fly   684 NGAGSGGYNSLPRNGGAQQLAQQSGLLEGH---DVVDDRGRSKK-------RNFFGTLKKRLS-- 736
                         ||  |....|:...|.|   ||...|.:|||       |:|||.||.|||
 Worm   658 -------------NG--QYYRDQTAPPEFHEELDVRQSRDKSKKAPTEKRDRSFFGELKDRLSGR 707

  Fly   737 --RSKTRTLSADQPNNNSHKSLSATNSNTTTATGFPRTATGTLNGDSSRSLSVDRATLSKSNSLG 799
              ||:.|:.|.|..||.                                       .|.::.||.
 Worm   708 RGRSQKRSKSVDVENNQ---------------------------------------LLEEAVSLP 733

  Fly   800 PRMGIGHSITDHSR-RSSIS------ESSAISGFSSASNKTYVHEASTLVLETIENGIKRHFIVP 857
            |.       .|.|| |.::|      |:.::.|.|..|.|: :::.|||:||..::...::|::|
 Worm   734 PS-------RDPSRTRYAVSSNDKYRETHSVGGRSGESTKS-LYQHSTLILELDQDKQAKYFLIP 790

  Fly   858 LAIAQRP---RWRRKGTKLHIYNDHTFIAKHLSG-SGLQCSICMKSIPRRPGKQGYECRDCQLIS 918
            .|:...|   |..|||.||||||||||:|..:.| ||..|::|.:.|.....||.|:||||:::.
 Worm   791 PAMLNEPAASRLMRKGKKLHIYNDHTFVAVKVKGCSGATCNVCQQRIRSSFSKQAYQCRDCKMVC 855

  Fly   919 HKQCHIRAPQACPNPTVLSMEL 940
            ||.||.:....|....|..:::
 Worm   856 HKTCHYKTDAFCTQSNVSKLQI 877

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10737	NP_001137711.1	SMP_SF	168..335	CDD:459248	36/186 (19%)
		C2_C21orf25-like	392..515	CDD:176060	48/125 (38%)
		C1_dGM13116p-like	874..932	CDD:410381	27/58 (47%)
tmem-24	NP_741753.1	SMP_SF	146..319	CDD:459248	35/183 (19%)
		C2_C21orf25-like	408..532	CDD:176060	48/123 (39%)
		C1_dGM13116p-like	810..869	CDD:410381	27/58 (47%)