Protein Alignment ena and vaspb

DIOPT Version :9

• Sequence 1: NP_001137709.1
• Gene: ena / 37201
• FlyBaseID: FBgn0000578
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: XP_005173736.1
• Gene: vaspb / 550487
• ZFINID: ZDB-GENE-030131-7118
• Length: 445
• Species: Danio rerio
• Alignment Length: 701
• Identity: 201/701 - (28%)
• Similarity: 272/701 - (38%)
• Gaps: 278/701 - (39%)

  Fly   298 AEQSIIGARASVMVYDDNQKKWVPSGSS-SGLSKVQIYHHQQNNTFRVVGRKLQ-DHEVVINCSI 360
            :|.||..|||:||:|||..|||||:|:. ...|:|||||:..||.|||||||:| |.:|||||.|
Zfish     2 SESSICQARATVMIYDDGSKKWVPAGTGPQAFSRVQIYHNPTNNAFRVVGRKMQTDQQVVINCPI 66

  Fly   361 LKGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGY 425
            :|||||||||..||||||::.|:||||.|:.||..||..|||||:|||    :.|.|
Zfish    67 VKGLKYNQATPNFHQWRDARQVWGLNFGSKEDAALFANGMMHALDVLS----SIPDG-------- 119

  Fly   426 EEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQP 490
                ||                       ||:
Zfish   120 ----GY-----------------------SAR--------------------------------- 124

  Fly   491 QQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMV 555
                                     |.|||          |:|::..||::.:||:.:||.::.:
Zfish   125 -------------------------PVSNG----------PSPEELEQQRRLEQQRLEQQERERL 154

  Fly   556 QAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLPSSASA 620
            :......::.::..                 |:.::|..:
Zfish   155 ERERQERERQERER-----------------QERERQERE------------------------- 177

  Fly   621 NSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQ 685
                                                  :|:.|.|...|.:||           .
Zfish   178 --------------------------------------RQERERPVASVVIPP-----------A 193

  Fly   686 VPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPP 750
            .||       .|||||||..|||||  |....|.||||.||....|||||||     ||.|.:..
Zfish   194 PPL-------APGGPPAPPGPPPPP--GPPPSGPPPPPGPPPSGGGAPPPPA-----PPLPSSGG 244

  Fly   751 AMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKEDPQADL--MGSLASQLQQIKLKKNKVTTSAPEN 813
            :.|||.|...||..|        .|..|..::.|:.|.  .|.:||....:...|    ..:..|
Zfish   245 SDGGGGPGGGGGLAA--------ALAAAKLRKVPKDDAGGGGGVASAAASVAAPK----ADSGRN 297

  Fly   814 SGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEK-KDPDPEAEVK----------- 866
            |.|..|.||.|     |....|...:|.||:..|||||..|:| :.|.|:||..
Zfish   298 SVSMPSGGGGG-----GGGGGGGGGLMGEMSAILARRRKAADKGEKPPPKAEEPANDDSDTQGPG 357

  Fly   867 --KRPWEKSNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFGSASEET 929
              :||||||.|:|                     .:..|..:..:....||....|....::|..
Zfish   358 DFRRPWEKSATMP---------------------RTNSAPRSLESPSSSSPLARMKPVSQSAEAE 401

  Fly   930 ILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR 980
                :|:|.|      :::.:|.|::.|:|.|:||||||||.|...|..:|
Zfish   402 ----SGEGES------EMERIKQELLEEVRKELQKVKNEIIGAFIQELQKR 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ena	NP_001137709.1	EVH1_Ena_VASP-like	301..408	CDD:269918	70/108 (65%)
		VASP_tetra	945..979	CDD:285929	15/33 (45%)
vaspb	XP_005173736.1	EVH1_Ena_VASP-like	5..114	CDD:269918	70/108 (65%)
		VASP_tetra	411..441	CDD:285929	15/29 (52%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575164
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001160
OrthoInspector	1	1.000	-	-		otm24633
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11202
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3391
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	8	7.830