Protein Alignment ena and vasp

DIOPT Version :9

• Sequence 1: NP_001137709.1
• Gene: ena / 37201
• FlyBaseID: FBgn0000578
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: NP_001008093.1
• Gene: vasp / 493455
• XenbaseID: XB-GENE-6454542
• Length: 378
• Species: Xenopus tropicalis
• Alignment Length: 707
• Identity: 175/707 - (24%)
• Similarity: 240/707 - (33%)
• Gaps: 357/707 - (50%)

  Fly   298 AEQSIIGARASVMVYDDNQKKWVPSGS-SSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSIL 361
            :|..::.|||:||||||:.||||.:|: :.|.|:|||:|:.....:||||||:||.:|||||.::
 Frog     2 SETPLVTARANVMVYDDSSKKWVAAGTGAQGPSRVQIFHNPTTQAYRVVGRKMQDQQVVINCPLV 66

  Fly   362 KGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYE 426
            :||||||||..|||||||:.|:||||:::.:|..||..:..||:.|
 Frog    67 RGLKYNQATPNFHQWRDSRQVWGLNFANKEEAGQFAVGITQALDAL------------------- 112

  Fly   427 EDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQ 491
                      |..|..|                        |||            :.|...:|:
 Frog   113 ----------ETGASTR------------------------IPQ------------NGPKVEEPE 131

  Fly   492 QQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQ 556
            |                             |::|                      ||:.:|.:
 Frog   132 Q-----------------------------PRRV----------------------QQEIEQRI- 144

  Fly   557 AGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLPSSASAN 621
                                                                             
 Frog   145 ----------------------------------------------------------------- 144

  Fly   622 SVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQV 686
                            |:|.||.||
 Frog   145 ----------------QSPVAPVMP---------------------------------------- 153

  Fly   687 PLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPA 751
                         .||||.||.||       |.||||.|       ||||   ||||..||||||
 Frog   154 -------------TPAPAAPPAPP-------GPPPPPGP-------PPPP---GGPPGGPPAPPA 188

  Fly   752 MGGGPPPAPGGPGAPPPPPPPPGLGGAPKKEDPQADLMGSLASQLQQIKLKKNKVTTSAPENSGS 816
                  |..|||  |||||.|.|.||.      .:.:.|.||:.|...||:  ||..:.....|.
 Frog   189 ------PTGGGP--PPPPPLPSGGGGG------SSGVSGGLAAALATAKLR--KVAKNDDAGGGG 237

  Fly   817 STSSGGSGNYGTIGRSSNGMAS-------MMDEMAKTLARRRAQAEKKDPDP------------- 861
            |:..||:.....|.|:|.|.|:       :|:||...||||:...::.:..|
 Frog   238 SSPVGGAPAKPDISRTSGGAATGGGGGGGLMEEMNAKLARRKMMTQQGERPPPTTTQDDNDIQAG 302

  Fly   862 --EAEVKKRPWEK-SNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFG 923
              ::::.:|||:: |.|||...|                         |..|...:|.|.
 Frog   303 RGQSDISRRPWDRGSTTLPRMKS-------------------------TVGSTEVAPSPE----- 337

  Fly   924 SASEETILKVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR 980
                               .:..::.:|.|::.|||.|:||||.|||:|...|..||
 Frog   338 -------------------DSDSMEKIKQELLEEMRRELQKVKEEIIEAFIQELRRR 375

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ena	NP_001137709.1	EVH1_Ena_VASP-like	301..408	CDD:269918	58/107 (54%)
		VASP_tetra	945..979	CDD:285929	15/33 (45%)
vasp	NP_001008093.1	EVH1_Ena_VASP-like	5..112	CDD:269918	58/106 (55%)
		VASP_tetra	340..375	CDD:370114	15/34 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001160
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR11202
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3391
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	4.130