Protein Alignment ena and ena

DIOPT Version :10

• Sequence 1: NP_001137709.1
• Gene: ena / 37201
• FlyBaseID: FBgn0000578
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: XP_061517395.1
• Gene: ena / 4577692
• VectorBaseID: AGAMI1_000674
• Length: 677
• Species: Anopheles gambiae
• Alignment Length: 769
• Identity: 381/769 - (49%)
• Similarity: 434/769 - (56%)
• Gaps: 179/769 - (23%)

  Fly   298 AEQSIIGARASVMVYDDNQKKWVPSGSSSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSILK 362
            :||||||||||||||||.|:||:|||||||||||||:||||||||||||||||||||||||||:|
Mosquito     2 SEQSIIGARASVMVYDDVQRKWIPSGSSSGLSKVQIFHHQQNNTFRVVGRKLQDHEVVINCSIIK 66

  Fly   363 GLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGN---- 423
            |||||||||||||||||||||||||||..|||.|||||||||:||||||..:.....||.|
Mosquito    67 GLKYNQATATFHQWRDSKFVYGLNFSSPMDAEAFARAMMHALDVLSGRVPPSSTMQTTNPNPSQM 131

  Fly   424 --GYEEDMGYRTMTSEDAAILRQN-----------------NSI----GGHVTPSAQTPTSQTNQ 465
              .|||||||||||.|||||::|.                 |||    ||.::|  |||||||
Mosquito   132 AAAYEEDMGYRTMTREDAAIMQQQQQMTSQPPGVGPPQQPPNSIPGPGGGILSP--QTPTSQT-- 192

  Fly   466 NNIP-------QSPPTPQGHHRTSSAPPAPQPQQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQ 523
              :|       |.....|.||||:||||.|.....||||||.|..|
Mosquito   193 --LPSQATQQQQQQQQQQTHHRTNSAPPVPPALPTQQQQQASQQSQ------------------- 236

  Fly   524 QVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMVQAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQ 588
                     .|||.||:.....||.......:..| ..||.|.||.||.||.|     ||...|.
Mosquito   237 ---------AQQQQQQKPIYASQQSNSSTNSITYG-NNSQPYPQPIYVASNQN-----HQMLNQS 286

  Fly   589 A-QQQPPQAPQPP-------LQNGGMYMVGHGHLPSSASAN--SVVYASQQQMLPQAHPQAPQAP 643
            . ..||||.|.||       |.||.:|...... ||:.::|  :.:||.|||::.|...|...||
Mosquito   287 VLPPQPPQQPPPPQQQLPSNLSNGSIYATATCS-PSATNSNPANPIYAGQQQLVSQQQQQQQSAP 350

  Fly   644 -----TMPGPGYGGPP--VPPPQQQAENPYGQVPMPP-PMNPSQQQQPGQVPLNRMSSQGGPGGP 700
                 .||..|| |||  |..|....:..||..|:|. ||.|..||||.    ::|.....|
Mosquito   351 PPPPMMMPPNGY-GPPNGVGGPYGAGQPQYGIPPVPQMPMQPPHQQQPP----SQMQQTNAP--- 407

  Fly   701 PAPAPPPP--PPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPPAMGGGPPPAPGGP 763
                ||||  ||.|..||     |.:.||               |||||.||.:...
Mosquito   408 ----PPPPMMPPMFPMAA-----PSSVPQ---------------PPAPPMPPNLNNA-------- 440

  Fly   764 GAPPPPPPPPGLGGAPKKEDPQADLMGSLASQLQQIKLKK-----------------------NK 805
            .||||||||||:......|      :.|||.||...|||:                       |.
Mosquito   441 AAPPPPPPPPGMPAVKPGE------INSLALQLASAKLKRSQPPKSSPAAGVSSTSSSANNGSNA 499

  Fly   806 VTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAE------ 864
            |:::..||||||||||||||||||||||:|||||||||||||||||||||||:||...:
Mosquito   500 VSSTVTENSGSSTSSGGSGNYGTIGRSSSGMASMMDEMAKTLARRRAQAEKKEPDSNEDGGAAGS 564

  Fly   865 -VKKRPWEKSNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKRFGSASEE 928
             .::|.||||:||||||  |:|:.:||.| .|||..||..|::.  ||.|||:|.||||||||||
Mosquito   565 GGRQRAWEKSSTLPHKL--GSGNNNAGGG-GGANSGSGQGGASL--SGSESPKPSRKRFGSASEE 624

  Fly   929 TILK-VN-GDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDAIKSEFNRR 980
            |||| :| ||..||..: .:.|.||.:|:||||.||.|.|.|||:|||||||||
Mosquito   625 TILKQINGGDSFSLPTA-VEFDNLKEDILREMRSEIAKAKQEIIEAIKSEFNRR 677

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ena	NP_001137709.1	EVH1_Ena_VASP-like	301..408	CDD:269918	97/106 (92%)
		VASP_tetra	946..979	CDD:462599	21/32 (66%)
ena	XP_061517395.1	None