DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ena and CG3588

DIOPT Version :9

Sequence 1:	NP_001137709.1	Gene:	ena / 37201	FlyBaseID:	FBgn0000578	Length:	980	Species:	Drosophila melanogaster
Sequence 2:	NP_570036.3	Gene:	CG3588 / 31278	FlyBaseID:	FBgn0025643	Length:	891	Species:	Drosophila melanogaster

Alignment Length:	583	Identity:	135/583 - (23%)
Similarity:	192/583 - (32%)	Gaps:	197/583 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   489 QPQQQQQQQQAQQM-GQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQ--QQQ----FQQQQ 546
            |||...||.|.||: .||                      |:.|...:|||  |||    :||.|
  Fly    30 QPQFAYQQPQFQQVYRQP----------------------QLQPQVYRQPQAYQQQPLVYYQQPQ 72

  Fly   547 QQQQYQQMV-------------QAGYAPSQQYQQPHYVLSNSNP--------NLTVHQYPTQ--- 587
            |.||::|..             |..:..:.:|.|.   :|||..        .:|..|..|:
  Fly    73 QPQQFRQRQGSVSKANTNAYERQVDFGNNLEYTQG---VSNSRAVTKQNGQRVVTKSQAQTRDVD 134

  Fly   588 ---------------QAQQQPPQ-----------------APQPPLQNG--------GMYMVGHG 612
                           .|..|..|                 :|| .||||        |...:|.|
  Fly   135 LGGLQLGNTLTRTRTNANGQVSQGIADQFRIGNVGLGASLSPQ-NLQNGFGLQRGADGDLRLGLG 198

  Fly   613 HLPSSASANSVVYASQQQMLPQAHPQAPQAPTMPGPG---------YGGPPVPPPQQQAENPYGQ 668
            .|......|    .:....|.||...|.......|..         :||..|...:..: |.:|:
  Fly   199 LLNLDLDRN----VANSNTLSQAQVNANGKGARAGSNSNSQSNTQHFGGVTVTDTRANS-NAFGK 258

  Fly   669 VPMPPPMNPSQQQQPGQVPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAP 733
            .            |.||.    .::.||.||..|.         .|.:.|||......|  |..|
  Fly   259 A------------QRGQT----SATTGGFGGNAAT---------NGQSFGGPFQRVVRQ--NRRP 296

  Fly   734 PP---------PAMGGGPPPAPPAPPAMGGGPP----PA-----PGGPGAPPPPPPPPGLGGAPK 780
            ..         |.:|.||..:|...|....|.|    |.     .||||...|....||.||...
  Fly   297 KRKAQFVPFGYPRIGFGPVLSPLERPRRQFGRPGFGGPGFGGEFGGGPGFGGPGFGGPGFGGPGF 361

  Fly   781 KE---DPQADLMGSLASQLQQIKLKKNKVTTSAPENS---------GSSTSSGGSGNYGTIGRSS 833
            ::   :|:.          ||.|.|.||.......|:         .||.:....||.|:...||
  Fly   362 EQEFYEPER----------QQHKKKGNKNQAHGNANAQGGPGFNQQASSNNHASPGNTGSSSISS 416

  Fly   834 N----GMASMMDEMAKTLARRRAQAE---KKDPDPEAE-VKKRPWEK------SNTLPHKLSGGA 884
            |    |.:..:.. |.|...:...|.   :.|.:.::: :..||.|:      :|| .|...|..
  Fly   417 NLAQDGSSGQVSS-ANTNTHQGQTANGGYQSDQNSQSQALNFRPGEQQASSANANT-QHTQQGNR 479

  Fly   885 GSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPMRKR--FGSASEETILK-VNGDGLSLALSN 944
            .:..:.||....|.|..|:.:||.|:..:..|...::  ...|:.::|.: .||.|.:.|.:|
  Fly   480 DTYDSNSGSTSTNNNKFGSATNTANTNSQVVRDGNRQDATSDANSQSIFQGNNGQGDASAQTN 542

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ena	NP_001137709.1	EVH1_Ena_VASP-like	301..408	CDD:269918
ena	NP_001137709.1	VASP_tetra	945..979	CDD:285929	135/583 (23%)
CG3588	NP_570036.3	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11202
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100