DRSC/TRiP Functional Genomics Resources

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Protein Alignment ena and Spred2

DIOPT Version :9

Sequence 1:NP_001137709.1 Gene:ena / 37201 FlyBaseID:FBgn0000578 Length:980 Species:Drosophila melanogaster
Sequence 2:NP_001040559.1 Gene:Spred2 / 305539 RGDID:1309304 Length:410 Species:Rattus norvegicus


Alignment Length:354 Identity:80/354 - (22%)
Similarity:130/354 - (36%) Gaps:77/354 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   302 IIGARASVMVYDDNQKKWVPSGSSSGLSKV---QIYHHQQN--NTFRVVGRKLQDHEVVINCSIL 361
            |:..:|.||..||:...|.|. ...|:|:|   ::.|.:.|  :.|.:.|.:.:|..||:.|.:.
  Rat    13 IVRVKAVVMTRDDSSGGWFPQ-EGGGISRVGVCKVMHPEGNGRSGFLIHGERQKDKLVVLECYVR 76

  Fly   362 KGLKYNQATATFHQWRDSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGYE 426
            |.|.|.:|..|||.|:.....:||.|.|..||..|.|.:..|:|.|   :..:.....|..|  |
  Rat    77 KDLVYTKANPTFHHWKVDNRKFGLTFQSPADARAFDRGVRKAIEDL---IEGSTTSSSTIHN--E 136

  Fly   427 EDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQPQ 491
            .::|              ::.:....|.|:...:.:...|....|.||...|.|..:..|.|...
  Rat   137 AELG--------------DDDVFTTATDSSSNSSQKREPNTRTISSPTSCEHRRIYTLDPYPMDL 187

  Fly   492 QQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQ------------PQQQQFQQ 544
            ....|:      .|.|:  |....|..:....::|      |:::            |.:.::..
  Rat   188 YHPDQR------LPRSY--PQVTFPEDDEEIVRIN------PREKIWMTGYEDYRHAPVRGKYLD 238

  Fly   545 QQQQQQYQQMVQAGYAPSQQYQQPHYVLSN-----SNPNLTVHQYPTQQAQQQPPQAPQPPLQNG 604
            ..:..........|..|..:|..| ||.|:     .:|...|       .:.|||:|.....:..
  Rat   239 STEDADSYVRFAKGEVPKHEYTYP-YVDSSDFGFGEDPKGNV-------IKTQPPRAKSRRRKEN 295

  Fly   605 G-----MY---MVGH-----GHLPSSASA 620
            |     :|   |..|     ||...:..|
  Rat   296 GERSRCVYCRDMFNHEENRRGHCQDAPDA 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
enaNP_001137709.1 EVH1_Ena_VASP-like 301..408 CDD:269918 37/110 (34%)
VASP_tetra 945..979 CDD:285929
Spred2NP_001040559.1 EVH1_SPRED-like 12..124 CDD:269978 38/114 (33%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 127..171 9/59 (15%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 274..294 6/26 (23%)
Sprouty 298..403 CDD:398746 6/27 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166335968
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG4590
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.740

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