Protein Alignment ena and unc-34

DIOPT Version :10

• Sequence 1: NP_001137709.1
• Gene: ena / 37201
• FlyBaseID: FBgn0000578
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: NP_503360.4
• Gene: unc-34 / 190098
• WormBaseID: WBGene00006770
• Length: 468
• Species: Caenorhabditis elegans
• Alignment Length: 706
• Identity: 162/706 - (22%)
• Similarity: 234/706 - (33%)
• Gaps: 291/706 - (41%)

  Fly   298 AEQSIIGARASVMVYDDNQKKWV-PSGSSSGLSKVQIYHHQQNNTFRVVGRKLQDHEVVINCSIL 361
            :|..|..|.|.||.|:::.|.|| ..|:...::.|::....:...||:|..: .|...::||:|.
 Worm     3 SEACIATAMARVMTYNESTKGWVLLGGNDDSMTNVRLIQDIRRPEFRIVSNR-ADSTNILNCNIY 66

  Fly   362 KGLKYNQATATFHQWR-DSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPPTNGNGY 425
            :|:||::||..||||| :.:.||||||.::.||..|...::.|:|.|.
 Worm    67 RGIKYHKATPMFHQWRTEQRRVYGLNFENEQDATMFLSIVLQAIETLK----------------- 114

  Fly   426 EEDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTSSAPPAPQP 490
            ..||
 Worm   115 VHDM------------------------------------------------------------- 118

  Fly   491 QQQQQQQQAQQMGQPGSHYGPTGNGPTSNGLPQQVNSQIPPAPQQQPQQQQFQQQQQQQQYQQMV 555
                                        ||:                           ..||||.
 Worm   119 ----------------------------NGI---------------------------SDYQQMH 128

  Fly   556 QAGYAPSQQYQQPHYVLSNSNPNLTVHQYPTQQAQQQPPQAPQPPLQNGGMYMVGHGHLPSSASA 620
            |.    ...||.||..|      :.:|..|....:.          ||...:.....|..|..|:
 Worm   129 QV----DNVYQDPHQHL------MHIHSAPNFHDEN----------QNAANFRKTSQHASSLLSS 173

  Fly   621 NSVVYASQQQMLPQAHPQAPQAPTMPGPGYGGPPVPPPQQQAENPYGQVPMPPPMNPSQQQQPGQ 685
            .:.....||:...|:        :....|...|..|||           |:|...|..|
 Worm   174 TAAALTQQQRRASQS--------SSTSAGSSIPHAPPP-----------PVPLTSNIPQ------ 213

  Fly   686 VPLNRMSSQGGPGGPPAPAPPPPPPSFGGAAGGGPPPPAPPQMFNGAPPPPAMGGGPPPAPPAPP 750
                              |||.|||..||.|         |...:|||||          ||.||
 Worm   214 ------------------APPAPPPPIGGIA---------PVNAHGAPPP----------PPLPP 241

  Fly   751 AMGGGPPPAPGGPGAPPPPPPPPGLGGAPKKEDPQADLMG-----SLASQL-----QQIKLKKNK 805
            .          |.||||||||||          |.|.||.     |||.||     |.:|...|.
 Worm   242 V----------GAGAPPPPPPPP----------PPAQLMASSGTPSLAEQLKMRSQQGLKATSNG 286

  Fly   806 VTTSAPENSGSSTSSGGSGNYGTIGRSSNGMASMMDEMAKTLARRRAQAEKKDPDPEAEVKKRPW 870
            |..:|.|  ....::.|:||             :|.|:...|.:|:....|.|...
 Worm   287 VKAAAAE--PEKPAAKGAGN-------------LMSELEAQLNKRKMTQAKSDAVD--------- 327

  Fly   871 EKSNTLPHKLSGGAGSGSAGSGHEGANGNSGGAGSNTTNSGGESPRPM----------------- 918
            .||||.......|.|:.::.:|...:||.|.|:.:....|..::.:||
 Worm   328 SKSNTSNGSSDSGCGTATSTNGCGSSNGGSVGSAAAKKWSVSDATKPMDSPKTHRKLPSASSLFS 392

  Fly   919 RKRFGSASEETIL--KVNGDGLSLALSNGDLDTLKAEIVREMRLEIQKVKNEIIDA 972
            ::...|:|..|:.  |...:|.|.|:.|..|:.|:|:|:.|||||:.|::..|::|
 Worm   393 QEDSSSSSSSTLTPSKPTTNGTSSAIPNDLLERLRADIMVEMRLEMNKLEQRIVEA 448

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ena	NP_001137709.1	EVH1_Ena_VASP-like	301..408	CDD:269918	39/108 (36%)
		VASP_tetra	946..979	CDD:462599	12/27 (44%)
unc-34	NP_503360.4	EVH1_Ena_VASP-like	6..114	CDD:269918	39/108 (36%)