Protein Alignment ena and SPRED1

DIOPT Version :9

• Sequence 1: NP_001137709.1
• Gene: ena / 37201
• FlyBaseID: FBgn0000578
• Length: 980
• Species: Drosophila melanogaster
• Sequence 2: XP_005254259.1
• Gene: SPRED1 / 161742
• HGNCID: 20249
• Length: 456
• Species: Homo sapiens
• Alignment Length: 225
• Identity: 72/225 - (32%)
• Similarity: 104/225 - (46%)
• Gaps: 47/225 - (20%)

  Fly   297 FAEQSIIGARASVMVYDDNQKKWVPSGSSSGLSKVQIYH--HQQNN---TFRVVGRKLQDHEVVI 356
            |...|....||.||..||:...|:|.| .||||.|.::.  ||:.|   .|.:.|.:|:|..||:
Human    21 FFHNSYARVRAVVMTRDDSSGGWLPLG-GSGLSSVTVFKVPHQEENGCADFFIRGERLRDKMVVL 84

  Fly   357 NCSILKGLKYNQATATFHQWR--DSKFVYGLNFSSQNDAENFARAMMHALEVLSGRVANNPGGPP 419
            .|.:.|.|.||:.|.|||.|:  |.||  ||.|.|..||..|.|.:..|:|.:|       .|.|
Human    85 ECMLKKDLIYNKVTPTFHHWKIDDKKF--GLTFQSPADARAFDRGIRRAIEDIS-------QGCP 140

  Fly   420 TNGNGYE--EDMGYRTMTSEDAAILRQNNSIGGHVTPSAQTPTSQTNQNNIPQSPPTPQGHHRTS 482
            .:.|..|  :|:   ....||::    ::.:..|:          ..|..:..|.|     :|:|
Human   141 ESKNEAEGADDL---QANEEDSS----SSLVKDHL----------FQQETVVTSEP-----YRSS 183

  Fly   483 SAPPAP----QPQQQQQQQQAQQM--GQPG 506
            :..|:|    ..::...|.||.|:  ||||
Human   184 NIRPSPFEDLNARRVYMQSQANQITFGQPG 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ena	NP_001137709.1	EVH1_Ena_VASP-like	301..408	CDD:269918	47/113 (42%)
		VASP_tetra	945..979	CDD:285929
SPRED1	XP_005254259.1	EVH1_SPRED-like	25..137	CDD:269978	48/121 (40%)
		Sprouty	345..440	CDD:282994

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165142469
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4590
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.740