DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15111 and abhd12

DIOPT Version :9

Sequence 1:	NP_725856.1	Gene:	CG15111 / 37200	FlyBaseID:	FBgn0034419	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001070065.1	Gene:	abhd12 / 767657	ZFINID:	ZDB-GENE-060929-268	Length:	382	Species:	Danio rerio

Alignment Length:	383	Identity:	136/383 - (35%)
Similarity:	210/383 - (54%)	Gaps:	61/383 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 VGLRCLQACL-------LIFFL-IFVVLPLIFRYSVTFQRGILFLTFIKYPKGLDLTKPESVGLY 86
            :|.||.:..|       ||:.| |::.:|:|.:...:.|..::||.|::.|..:||.:|:..|:.
Zfish    45 MGRRCRRGGLMWRLRRILIWLLGIYIAIPVIIKVCPSIQAKLVFLNFVRVPYFIDLKRPQDQGMN 109

  Fly    87 ATRNFYITVKDHDQDEDGVRVGVWHVLPSNAVRRFKRELRVEEEVAQDPDQQLDPAPGNERELKE 151
            .|.|||:      |.|:|:.:||||.:|:...|         |..|:|.:
Zfish   110 HTHNFYL------QPEEGINIGVWHTVPAGMWR---------EAQAKDAE--------------- 144

  Fly   152 LSPAIRSEFPVVLPENEQLFYERLLRMPGGTVVLYLHGNTASRGSGHRSEVYKLLRKLNYHVFSF 216
                               :||:..: ....|:||||||..:||..||.::||:|..|.|||.:|
Zfish   145 -------------------WYEKSFQ-SSHPVILYLHGNAGTRGGDHRVQLYKVLSSLGYHVVTF 189

  Fly   217 DYRGYADSDPVPPTEEGVVRDAMMVFEYIANTTS-NPIVVWGHSLGTGVATHLCAKLASLRERAP 280
            ||||:.||:. .|:|.|:..||:.::::|..... .|:.:|||||||||||:|..:|.. |...|
Zfish   190 DYRGWGDSEG-SPSERGMTSDALFLYQWIKQRIGPKPLYIWGHSLGTGVATNLVRRLCD-RGTPP 252

  Fly   281 RGVILESPFTNIRDEIRMHPFAKLYKNLPWFNFTISQPMYTNRLRFESDVHVLEFRQPIMIIHAE 345
            ..:||||||||||:|.:.|||:.:|:.||.|::.....:..|.:||.||.:|.....|::|:|||
Zfish   253 DALILESPFTNIREEAKSHPFSMVYRYLPGFDWFFLDAISANDIRFASDENVNHISCPVLILHAE 317

  Fly   346 DDVVVPFNLGYRLYRIALDGRSRTSGPVEFHRFGASRKYGHKYLCRAPELPGLIQKFV 403
            ||.||||.||.:||.:|...:|.....|:|..|.:|..|.||::.::|:||.::..|:
Zfish   318 DDTVVPFQLGKKLYDLAAQSKSLNGHKVQFIPFSSSLGYRHKFIYKSPQLPNILSDFL 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15111	NP_725856.1	Abhydrolase_5	183..381	CDD:289465	91/198 (46%)
abhd12	NP_001070065.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..45		136/383 (36%)
abhd12	NP_001070065.1	Hydrolase_4	151..340	CDD:378820	87/191 (46%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594470
Domainoid	1	1.000	131	1.000	Domainoid score	I5121
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22910
Inparanoid	1	1.050	242	1.000	Inparanoid score	I3296
OMA	1	1.010	-	-		QHG45520
OrthoDB	1	1.010	-	-		D385100at33208
OrthoFinder	1	1.000	-	-		FOG0005082
OrthoInspector	1	1.000	-	-		otm24425
orthoMCL	1	0.900	-	-		OOG6_103844
Panther	1	1.100	-	-	LDO	PTHR12277
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4218
SonicParanoid	1	1.000	-	-		X2277
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800