DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG15111 and Abhd12

DIOPT Version :9

Sequence 1:	NP_725856.1	Gene:	CG15111 / 37200	FlyBaseID:	FBgn0034419	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001019485.1	Gene:	Abhd12 / 499913	RGDID:	1562570	Length:	398	Species:	Rattus norvegicus

Alignment Length:	373	Identity:	141/373 - (37%)
Similarity:	209/373 - (56%)	Gaps:	56/373 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 LRCLQACLLIFFLIFVVLPLIFRYSVTFQRGILFLTFIKYPKGLDLTKPESVGLYATRNFYITVK 96
            ||.:..|:|.|   ::.:|.:.:.....|..::||.|::.|..:||.||:..||..|.|:|:
  Rat    72 LRKILLCVLGF---YIAIPFLVKLCPGIQAKLIFLNFVRVPYFIDLKKPQDQGLNHTCNYYL--- 130

  Fly    97 DHDQDEDGVRVGVWHVLPSNAVRRFKRELRVEEEVAQDPDQQLDPAPGNERELKELSPAIRSEFP 161
               |.||.|.:||||.:||           |..:.||..|
  Rat   131 ---QPEDDVTIGVWHTIPS-----------VWWKNAQGKD------------------------- 156

  Fly   162 VVLPENEQLFYERLLRMPGGTVVLYLHGNTASRGSGHRSEVYKLLRKLNYHVFSFDYRGYADSDP 226
                   |::||..| .....::||||||..:||..||.|:||:|..|.|||.:|||||:.||..
  Rat   157 -------QMWYEDAL-ASNHPIILYLHGNAGTRGGDHRVELYKVLSSLGYHVVTFDYRGWGDSVG 213

  Fly   227 VPPTEEGVVRDAMMVFEYI-ANTTSNPIVVWGHSLGTGVATHLCAKLASLRERAPRGVILESPFT 290
            . |:|.|:..||:.||::| |.:..||:.:|||||||||||:|..:|.. ||..|..:|||||||
  Rat   214 T-PSERGMTYDALHVFDWIKARSGDNPVYIWGHSLGTGVATNLVRRLCE-RETPPDALILESPFT 276

  Fly   291 NIRDEIRMHPFAKLYKNLPWFNFTISQPMYTNRLRFESDVHVLEFRQPIMIIHAEDDVVVPFNLG 355
            |||:|.:.|||:.:|:..|.|::....|:.::.::|.:|.::.....|::|:|||||.||||:||
  Rat   277 NIREEAKSHPFSVIYRYFPGFDWFFLDPITSSGIKFANDENMKHISCPLLILHAEDDPVVPFHLG 341

  Fly   356 YRLYRIALDGRSRTSGPVEFHRFGASRKYGHKYLCRAPELPGLIQKFV 403
            .:||.||...||.....|:|..|.:...|.|||:.::||||.::::|:
  Rat   342 RKLYNIAAPSRSFRDFKVQFIPFHSDLGYRHKYIYKSPELPRILREFL 389

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15111	NP_725856.1	Abhydrolase_5	183..381	CDD:289465	94/198 (47%)
Abhd12	NP_001019485.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..24
Abhd12	NP_001019485.1	Hydrolase_4	165..372	CDD:378820	95/208 (46%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	133	1.000	Domainoid score	I4949
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H22910
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3194
OMA	1	1.010	-	-		QHG45520
OrthoDB	1	1.010	-	-		D385100at33208
OrthoFinder	1	1.000	-	-		FOG0005082
OrthoInspector	1	1.000	-	-		oto96870
orthoMCL	1	0.900	-	-		OOG6_103844
Panther	1	1.100	-	-	LDO	PTHR12277
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2277
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	15	14.840