DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15111 and Acot6

DIOPT Version :9

Sequence 1:	NP_725856.1	Gene:	CG15111 / 37200	FlyBaseID:	FBgn0034419	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_766168.1	Gene:	Acot6 / 217700	MGIID:	1921287	Length:	419	Species:	Mus musculus

Alignment Length:	442	Identity:	86/442 - (19%)
Similarity:	144/442 - (32%)	Gaps:	166/442 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 PLIFRYSVTFQRGILFLTFIKYPKG----LDLTKPESVGLYATRNFYITVKDHDQDEDGVRVG-- 108
            |:..|..:..::|:||....:|...    |||.:..::|                   |...|
Mouse    31 PVTLRSVLRDEKGMLFRAHARYRADSHGELDLARTPALG-------------------GSFSGLE 76

  Fly   109 ----VWHVLPSNAV-RRFKRELR----VEEEV--AQDPD--QQLDPAPGNERELKELSPAIRSEF 160
                :|.:.|.... |..||:::    ||.||  ..:||  |:|..|. :||..  ::|.:|.
Mouse    77 PMGLLWAMEPDRPFWRLIKRDVQIPFVVELEVLDGHEPDGGQRLARAV-HERHF--MAPGVRR-- 136

  Fly   161 PVVLPENEQLFYERLLRMPG-----GTVVLY-----LHGNTASRGSGHRSEVYKLLRKLNYHVFS 215
               :|..|......|...||     |.:.||     |..:.||..:||...|..|
Mouse   137 ---VPVREGRVRATLFLPPGKGQFPGIIDLYGSIGGLCEHRASLLAGHGFAVLAL---------- 188

  Fly   216 FDYRGYADSDPVPPTEEGVVRDAMMVF--EYIANTTSNPIVVWGHSLG-TGVA--THLCAKLAS- 274
                .|...:.:|..    :.|..:.:  |.:|....:| .|.|.::| .||:  ..||..:|:
Mouse   189 ----AYFQFEDLPEN----LSDVRLEYFEEALALMLRHP-QVKGPNIGLIGVSKGADLCLSMAAF 244

  Fly   275 LRERAPRGVILESPFTNIRDEIRMHPFAKLYKNL--------------------PWFNFTISQPM 319
            |::.....|::.:...|     .:.|.  .||:|                    ..:|..:.:|.
Mouse   245 LKDNITATVLINACVAN-----TLVPL--YYKDLFVPELGCDQTKNKSGLMDLRDMWNNPLEEPN 302

  Fly   320 YTNRLRFE------------------SDV--------------------------HVLE---FRQ 337
            :.:.:..|                  |||                          |.:|   |..
Mouse   303 HQSLIPLEKAQGPFLFLVGMDDHNWKSDVYARIACERLQAHGKDRPQIIYYPETGHCIEPPYFPP 367

  Fly   338 PIMIIHAEDDVVVPFNLGYRLYRIALDGRSRTSGPVEFHRFGASRKYGHKYL 389
            ||..:|        |.||..::.   .|:.|.....:...:...:.:..|||
Mouse   368 PIATVH--------FVLGEAVFN---GGKPRAQSRAQLDAWQRIQTFFQKYL 408

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15111	NP_725856.1	Abhydrolase_5	183..381	CDD:289465	47/275 (17%)
Acot6	NP_766168.1	Bile_Hydr_Trans	17..137	CDD:282610	30/132 (23%)
		Aes	83..374	CDD:223730	65/332 (20%)
		BAAT_C	203..410	CDD:285986	38/225 (17%)
		Microbody targeting signal. /evidence=ECO:0000255	417..419
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900