DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG15111 and Acnat2

DIOPT Version :9

Sequence 1:	NP_725856.1	Gene:	CG15111 / 37200	FlyBaseID:	FBgn0034419	Length:	411	Species:	Drosophila melanogaster
Sequence 2:	NP_001343218.1	Gene:	Acnat2 / 209186	MGIID:	2444345	Length:	420	Species:	Mus musculus

Alignment Length:	380	Identity:	77/380 - (20%)
Similarity:	134/380 - (35%)	Gaps:	108/380 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 KPESVGLYATRNFYITVKDHDQDED------GVRVGV------WHVLPSNAVRRFKRE------- 124
            |.|:..::.::.||.|.:..:.|.:      |..|||      :.:.|..|..|..::
Mouse    38 KDENDNVFQSQAFYKTNEAGEVDLEKTPALGGDYVGVHPMGLFFSLKPKKAFHRLMKKDVMNSPL 102

  Fly   125 ---------------LRVEEEVAQDPDQQLDPAPGNERE-LKE-------LSPAIRSEFPVVLPE 166
                           :|:..:.:|.. |:....||.:|| ::|       ..|..:..||.::.
Mouse   103 CICLDLYDSVNWLETVRIPSKASQRV-QRWFVGPGVKREQIQEGRVRGALFLPPGKGPFPGIID- 165

  Fly   167 NEQLFYERLLRMPGGTVVLYLHGNTASRGSGHRSEVYKLLRKLNYHVFSFDYRGYADSDPVPPTE 231
                    |..:.||.|..        |.|        ||....:.|.:..|..|.|. |..|.|
Mouse   166 --------LFGLIGGLVEF--------RAS--------LLASHGFAVLALAYFAYEDL-PEKPQE 205

  Fly   232 EGVVRDAMMVFEYIAN-TTSNPIVVW----------GHSLGTGVATHLCAKLASLRERAPRGV-- 283
            ..     :..||..|| ..|:|.:..          |..:|..:|.:|...:|::....|..:
Mouse   206 VD-----LEYFEEAANFLLSHPKIQQPGIGVISTSKGAEIGLAMACYLKQVIATVCINGPTTITI 265

  Fly   284 -------ILESPFTNIRDEIRMHPFAKLYKNLPWFNFTISQPMYTNRLRFESDVHVLEFRQPIMI 341
                   ::.:|.....:.|::|....|.     |.:| :|.:: |:|..::.:.|.:.:..|:.
Mouse   266 FPLRYQDLVMTPIHPALERIQVHDSGALL-----FRYT-TQYLH-NKLNSQNILPVEKAQGKILF 323

  Fly   342 IHAEDDVVVPFNLGYRLYRIALDGRSRTSGPVEFHRFGASRKYGHKYLCRAPELP 396
            |..|:|..:...|..:.....|....|:||     |..|....||  |...|..|
Mouse   324 IVGENDECLDSKLHAQKAMDRLQRHGRSSG-----RMLAYPGAGH--LIEPPYSP 371

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG15111	NP_725856.1	Abhydrolase_5	183..381	CDD:289465	44/217 (20%)
Acnat2	NP_001343218.1	Bile_Hydr_Trans	15..139	CDD:309767	18/101 (18%)
		BAAT_C	206..415	CDD:312395	38/185 (21%)
		Microbody targeting signal	418..420
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1073
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900